دورية أكاديمية
Challenges in cell transplantation for muscular dystrophy
| العنوان: | Challenges in cell transplantation for muscular dystrophy |
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| المؤلفون: | Galli, F., Mouly, V., Butler-Browne, G., Cossu, G. |
| بيانات النشر: | Elsevier |
| سنة النشر: | 2021 |
| المجموعة: | Max-Delbrueck-Center for Molecular Medicine, Berlin: MDC Repository |
| مصطلحات موضوعية: | Function and Dysfunction of the Nervous System, Topic 3: Integrative Biomedicine |
| الوصف: | For decades now, cell transplantation has been considered a possible therapeutic strategy for muscular dystrophy, but failures have largely outnumbered success or at least encouraging outcomes. In this review we will briefly recall the history of cell transplantation, discuss the peculiar features of skeletal muscle, and dystrophic skeletal muscle in particular, that make the procedure complicated and inefficient. As there are many recent and exhaustive reviews on the various myogenic cell types that have been or will be transplanted, we will only briefly describe them and refer the reader to these reviews. Finally, we will discuss possible strategies to overcome the hurdles that prevent biological efficacy and hence clinical success. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | http://edoc.mdc-berlin.de/21082/1/21082oa.pdfTest; Challenges in cell transplantation for muscular dystrophy. Galli, F. and Mouly, V. and Butler-Browne, G. and Cossu, G. Experimental Cell Research 409 (1): 112908. 1 December 2021 |
| DOI: | 10.1016/j.yexcr.2021.112908 |
| الإتاحة: | https://doi.org/10.1016/j.yexcr.2021.112908Test http://edoc.mdc-berlin.de/21082Test/ https://edoc.mdc-berlin.de/21082Test/ http://edoc.mdc-berlin.de/21082/1/21082oa.pdfTest |
| حقوق: | cc_by_nc_nd_4 |
| رقم الانضمام: | edsbas.808A6F47 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.yexcr.2021.112908 |
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