دورية أكاديمية
Fermentative Butanol Production by Clostridia
| العنوان: | Fermentative Butanol Production by Clostridia |
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| المؤلفون: | Sang Up Lee, Jin Hwan Park, Seh Hee Jang, Nielsen, Lars K., Jaehyun Kim, Kwang S.Jung |
| المساهمون: | Douglas S. Clark |
| بيانات النشر: | Wiley |
| سنة النشر: | 2008 |
| المجموعة: | The University of Queensland: UQ eSpace |
| مصطلحات موضوعية: | butanol • metabolic engineering • Clostridium • systems biotechnology, C1, 8699 Other Manufacturing, 100303 Fermentation, 100306 Industrial Molecular Engineering of Nucleic Acids and Proteins |
| الوصف: | Butanol is an aliphatic saturated alcohol having the molecular formula of C4H9OH. Butanol can be used as an intermediate in chemical synthesis and as a solvent for a wide variety of chemical and textile industry applications. Moreover, butanol has been considered as a potential fuel or fuel additive. Biological production of butanol (with acetone and ethanol) was one of the largest industrial fermentation processes early in the 20th century. However, fermentative production of butanol had lost its competitiveness by 1960s due to increasing substrate costs and the advent of more efficient petrochemical processes. Recently, increasing demand for the use of renewable resources as feedstock for the production of chemicals combined with advances in biotechnology through omics, systems biology, metabolic engineering and innovative process developments is generating a renewed interest in fermentative butanol production. This article reviews biotechnological production of butanol by clostridia and some relevant fermentation and downstream processes. The strategies for strain improvement by metabolic engineering and further requirements to make fermentative butanol production a successful industrial process are also discussed. Biotechnol. Bioeng. 2008;101: 209-228. © 2008 Wiley Periodicals, Inc. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 0006-3592 |
| العلاقة: | orcid:0000-0001-8191-3511; 09-03-01066-a |
| الإتاحة: | https://doi.org/10.1002/bit.22003Test https://espace.library.uq.edu.au/view/UQ:174171Test |
| رقم الانضمام: | edsbas.80797B84 |
| قاعدة البيانات: | BASE |
| تدمد: | 00063592 |
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