دورية أكاديمية
Schistosomiasis vaccines: where do we stand?
| العنوان: | Schistosomiasis vaccines: where do we stand? |
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| المؤلفون: | Tebeje, Biniam Mathewos, Harvie, Marina, You, Hong, Loukas, Alex, McManus, Donald P. |
| بيانات النشر: | BioMed Central |
| سنة النشر: | 2016 |
| المجموعة: | The University of Queensland: UQ eSpace |
| مصطلحات موضوعية: | Antigen discovery, Immune protection, Immune response, Schistosoma haematobium, Schistosoma japonicum, Schistosoma mansoni, Schistosomiasis, Vaccine |
| الوصف: | Schistosomiasis, caused mainly by S. mansoni, S. haematobium and S. japonicum, continues to be a serious tropical disease and public health problem resulting in an unacceptably high level of morbidity in countries where it is endemic. Praziquantel, the only drug currently available for treatment, is unable to kill developing schistosomes, it does not prevent re-infection and its continued extensive use may result in the future emergence of drug-resistant parasites. This scenario provides impetus for the development and deployment of anti-schistosome vaccines to be used as part of an integrated approach for the prevention, control and eventual elimination of schistosomiasis. This review considers the present status of candidate vaccines for schistosomiasis, and provides some insight on future vaccine discovery and design. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1756-3305 |
| العلاقة: | Not set |
| الإتاحة: | https://doi.org/10.1186/s13071-016-1799-4Test https://espace.library.uq.edu.au/view/UQ:409569Test |
| رقم الانضمام: | edsbas.8037FF55 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 17563305 |
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