التفاصيل البيبلوغرافية
| العنوان: |
Air Pollution Exposure During Pregnancy and Symptoms of Attention Deficit and Hyperactivity Disorder in Children in Europe |
| المؤلفون: |
Forns, Joan, Sunyer, Jordi, Garcia-Esteban, Raquel, Porta, Daniela, Ghassabian, Akhgar, Giorgis-Allemand, Lise, Gong, Tong, Gehring, Ulrike, Sørensen, Mette, Standl, Marie, Sugiri, Dorothee, Almqvist, Catarina, Andiarena, Ainara, Badaloní, Chiara, Beelen, Rob, Berdel, Dietrich, Cesaroni, Giulia, Charles, Marie-Aline, Eriksen, Kirsten Thorup, Estarlich, Marisa, Fernandez, Mariana F, Forhan, Anne, Jaddoe, Vincent W V, Korek, Michal, Lichtenstein, Paul, Lertxundi, Aitana, Lopez-Espinosa, Maria-Jose, Markevych, Iana, de Nazelle, Audrey, Raaschou-Nielsen, Ole, Nieuwenhuijsen, Mark, Pérez-Lobato, Rocío, Philippat, Claire, Slama, Rémy, Tiesler, Carla M T, Verhulst, Frank C, von Berg, Andrea, Vrijkotte, Tanja, Nybo Andersen, Anne-Marie, Heude, Barbara, Krämer, Ursula, Heinrich, Joachim, Tiemeier, Henning, Forastiere, Francesco, Pershagen, Göran, Brunekreef, Bert, Guxens, Mònica |
| المساهمون: |
One Health Chemisch, dIRAS RA-2, LS IRAS EEPI ME (Milieu epidemiologie) |
| سنة النشر: |
2018 |
| مصطلحات موضوعية: |
attention deficit disorder with hyperactivity, child development, environmental pollution, longitudinal studies, meta-analysis, nitrogen oxides, particulate matter, prospective studies, Taverne |
| الوصف: |
BACKGROUND: Exposure to air pollution during pregnancy may increase attention-deficit/hyperactivity disorder (ADHD) symptoms in children, but findings have been inconsistent. We aimed to study this association in a collaborative study of eight European population-based birth/child cohorts, including 29,127 mother-child pairs. METHODS: Air pollution concentrations (nitrogen dioxide [NO2] and particulate matter [PM]) were estimated at the birth address by land-use regression models based on monitoring campaigns performed between 2008 and 2011. We extrapolated concentrations back in time to exact pregnancy periods. Teachers or parents assessed ADHD symptoms at 3-10 years of age. We classified children as having ADHD symptoms within the borderline/clinical range and within the clinical range using validated cutoffs. We combined all adjusted area-specific effect estimates using random-effects meta-analysis and multiple imputations and applied inverse probability-weighting methods to correct for loss to follow-up. RESULTS: We classified a total of 2,801 children as having ADHD symptoms within the borderline/clinical range, and 1,590 within the clinical range. Exposure to air pollution during pregnancy was not associated with a higher odds of ADHD symptoms within the borderline/clinical range (e.g., adjusted odds ratio [OR] for ADHD symptoms of 0.95, 95% confidence interval [CI] = 0.89, 1.01 per 10 µg/m increase in NO2 and 0.98, 95% CI = 0.80, 1.19 per 5 µg/m increase in PM2.5). We observed similar associations for ADHD within the clinical range. CONCLUSIONS: There was no evidence for an increase in risk of ADHD symptoms with increasing prenatal air pollution levels in children aged 3-10 years. See video abstract at, http://links.lww.com/EDE/B379Test. |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| تدمد: |
1044-3983 |
| العلاقة: |
https://dspace.library.uu.nl/handle/1874/374744Test |
| الإتاحة: |
https://dspace.library.uu.nl/handle/1874/374744Test |
| حقوق: |
info:eu-repo/semantics/OpenAccess |
| رقم الانضمام: |
edsbas.7F400005 |
| قاعدة البيانات: |
BASE |
