دورية أكاديمية
Family history of diabetes and risk of atherosclerotic cardiovascular disease in Korean men and women
| العنوان: | Family history of diabetes and risk of atherosclerotic cardiovascular disease in Korean men and women |
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| المساهمون: | Ji Wan Park, Ji Eun Yun, Taesung Park, Eorin Cho, Sun Ha Jee, Yangsu Jang, Terri H. Beaty, Jonathan M. Samet, Yun, Ji Eun, Jang, Yang Soo, Jee, Sun Ha |
| سنة النشر: | 2008 |
| مصطلحات موضوعية: | Adult, Aged, 80 and over, Asian Continental Ancestry Group/statistics & numerical data, Atherosclerosis/ethnology, Cohort Studies, Diabetes Mellitus, Type 2/ethnology, Family Health, Female, Follow-Up Studies, Humans, Korea/epidemiology, Male, Middle Aged, Proportional Hazards Models, Risk Factors, Sex Distribution, Family history of diabetes, Cardiovascular disease, Cohort study |
| الوصف: | The importance of family history of type 2 diabetes (FHD) as a risk factor for atherosclerotic cardiovascular disease (ASCVD) remains controversial. A report of diabetes in parents and siblings was used to establish FHD in a cohort of 1,005,230 Koreans aged 30-95 years insured by the National Health Insurance Corporation who had a biennial medical evaluation during 1992-1995. ASCVD morbidity and mortality from 1993 to 2005 were examined in relation to FHD and other ASCVD risk factors. The risk of ischemic heart disease (IHD) increased significantly (19%) in men with FHD but not in women. A strong interaction was observed between FHD and personal history of diabetes for the occurrence of ASCVD; men with both diabetes and FHD were at significantly increased risk of developing IHD, cerebrovascular disease and ASCVD with hazard ratios (HR) of 2.28, 2.07, and 2.12, respectively, compared to those who had neither FHD nor type 2 diabetes. Corresponding risks were 2.64, 2.03, and 2.10 in women, respectively. This study demonstrates that risk of ASCVD is increased among those with diabetes and a family history of diabetes; suggesting that genetic factors associated with occurrence of familial diabetes may increase risk of ASCVD beyond the risk among people without FHD ; open |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | 224~231 |
| اللغة: | unknown |
| تدمد: | 0021-9150 1879-1484 17493625 |
| العلاقة: | ATHEROSCLEROSIS; J00260; OAK-2008-00352; https://ir.ymlib.yonsei.ac.kr/handle/22282913/106472Test; http://www.sciencedirect.com/science/article/pii/S0021915007001967Test; T200800320; ATHEROSCLEROSIS, Vol.197(1) : 224-231, 2008 |
| DOI: | 10.1016/j.atherosclerosis.2007.03.037 |
| الإتاحة: | https://doi.org/10.1016/j.atherosclerosis.2007.03.037Test https://ir.ymlib.yonsei.ac.kr/handle/22282913/106472Test http://www.sciencedirect.com/science/article/pii/S0021915007001967Test |
| حقوق: | CC BY-NC-ND 2.0 KR ; https://creativecommons.org/licenses/by-nc-nd/2.0/krTest/ ; not free |
| رقم الانضمام: | edsbas.7BB82DC3 |
| قاعدة البيانات: | BASE |
| تدمد: | 00219150 18791484 17493625 |
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| DOI: | 10.1016/j.atherosclerosis.2007.03.037 |