دورية أكاديمية
Left atrial mechanics in patients with acute STEMI and secondary mitral regurgitation: A prospective pilot CMR feature tracking study
| العنوان: | Left atrial mechanics in patients with acute STEMI and secondary mitral regurgitation: A prospective pilot CMR feature tracking study |
|---|---|
| المؤلفون: | Lapinskas, Tomas, Bučius, Paulius, Urbonaitė, Laura, Stabinskaitė, Agnieta, Valuckienė, Živilė, Jankauskaitė, Lina, Benetis, Rimantas, Žaliūnas, Remigijus |
| المصدر: | Medicina, Wrocław : Elsevier, 2017, vol. 53, no. 1, p. 11-18 ; ISSN 1010-660X ; eISSN 1648-9144 |
| سنة النشر: | 2017 |
| المجموعة: | LSRC VL (Lithuanian Social Research Centre Virtual Library) / LSTC VB (Lietuvos socialinių tyrimų centras virtualią biblioteką) |
| مصطلحات موضوعية: | Mitral valve insufficiency, Myocardium, pathology, Heart atria, diagnostic imaging, Magnetic resonance imaging, methods, info:eu-repo/classification/udc/616.127 |
| الوصف: | Background and objective: Left atrium (LA) is an important biomarker of adverse cardiovascular outcomes and cerebrovascular events. This study aimed to evaluate LA myocardial deformation using cardiac magnetic resonance feature tracking (CMR-FT) in patients with acute ST-segment elevation myocardial infarction (STEMI) and secondary mitral regurgita- tion (MR). Additionally, to assess interobserver and intraobserver variability of the technique. Materials and methods: Twenty patients with STEMI underwent CMR with a 1.5 Tesla MRI scanner. According to the presence of MR patients were divided into two groups: MR(+) and MR( ). Total LA strain (es), passive LA strain (ee), and active LA strain (ea) were obtained. Additionally, total, passive and active strain rates (SRs, SRe, and SRa) were calculated. To assess interobserver agreement data analysis was performed by second independent observer. Results: LA volumetric and functional parameters were similar in both groups. All LA strain values were significantly higher in patients with MR: es (27.67 10.25 for MR( ) vs. 32.80 6.95 for MR(+); P = 0.01), ee (15.29 7.30 for MR( ) vs. 19.22 6.04 for MR(+); P = 0.01) and ea (12.38 4.23 for MR( ) vs. 14.44 5.19 for MR(+); P = 0.03). Only SRe significantly increased in patients with MR ( 0.57 0.24 for MR( ) vs. 0.70 0.20 for MR(+); P = 0.01). All LA deformation parameters demonstrated high interobserver and intraobserver agreement. Conclusions: Conventional volumetric and functional LA parameters do not detect early changes in LA performance in patients with STEMI and secondary MR. In contrast, LA reservoir, passive and active strain are significantly higher in patients with MR. Only peak early negative strain rate substantially increases during secondary MR. LA deformation parameters derived from conventional cine images using CMR-FT technique are highly reproducible. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | http://lsmu.oai.elaba.lt/documents/21047542.pdfTest; http://lsmu.lvb.lt/LSMU:ELABAPDB21047542&prefLang=en_USTest |
| الإتاحة: | https://doi.org/10.1016/j.medici.2017.02.001Test http://lsmu.oai.elaba.lt/documents/21047542.pdfTest http://lsmu.lvb.lt/LSMU:ELABAPDB21047542&prefLang=en_USTest |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.7AA58ED1 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |