دورية أكاديمية
[Kappa light chain deposition disease, presenting as Sjögren's syndrome, successfully treated by high-dose melphalan and autologous blood stem transplantation]
| العنوان: | [Kappa light chain deposition disease, presenting as Sjögren's syndrome, successfully treated by high-dose melphalan and autologous blood stem transplantation] |
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| المؤلفون: | Foguem, C., Kantelip, Bernadette, Deconinck, Eric, Hafsaoui, Chafika, Méaux-Ruault, Nadine, Gil, Helder, Magy-Bertrand, Nadine, Dupond, Jean-Louis |
| المساهمون: | Service d'hématologie, Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), Service d'Oncologie Médicale CHRU Besançon, Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté COMUE (UBFC)-Université Bourgogne Franche-Comté COMUE (UBFC), Service d'Anatomie pathologique CHRU Besançon, Interactions hôte-greffon-tumeur, ingénierie cellulaire et génique - UFC (UMR INSERM 1098) (RIGHT), Institut National de la Santé et de la Recherche Médicale (INSERM)-Etablissement français du sang Bourgogne-Franche-Comté (EFS BFC)-Université de Franche-Comté (UFC) |
| المصدر: | ISSN: 0248-8663. |
| بيانات النشر: | HAL CCSD Elsevier |
| سنة النشر: | 2009 |
| المجموعة: | Université de Franche-Comté (UFC): HAL |
| مصطلحات موضوعية: | MESH: Biopsy, MESH: Diagnosis, Differential, MESH: Salivary Glands, MESH: Sialography, MESH: Sjogren's Syndrome, MESH: Stem Cell Transplantation, MESH: Tomography, X-Ray Computed, MESH: Transplantation, Autologous, MESH: Electromyography, MESH: Female, MESH: Humans, MESH: Hypertrophy, MESH: Immunoglobulin kappa-Chains, MESH: Melphalan, MESH: Paraproteinemias, MESH: Peripheral Nervous System Diseases, [SDV.IMM]Life Sciences [q-bio]/Immunology |
| الوصف: | International audience ; INTRODUCTION: Light chain deposition disease is a systemic disorder characterised by tissue deposition of monoclonal immunoglobulin light chains without tinctorial properties. It has been exceptionally reported with salivary involvement mimicking Sjögren's syndrome and peripheral neuropathy. CASE REPORT: We report a case of light chain deposition disease associated with plasma cell dyscrasia presenting as sicca syndrome with salivary glands hypertrophy and polyneuropathy successfully treated by high dose melphalan and autologous blood stem transplantation. CONCLUSION: Light chain deposition disease should be recognized as an aetiology of sicca syndrome and peripheral neuropathy. Further studies should assess the prevalence of sicca syndrome in light chain deposition disease and better characterise the neurological manifestations. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | French |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/18801600; inserm-00484589; https://www.hal.inserm.fr/inserm-00484589Test; PUBMED: 18801600 |
| DOI: | 10.1016/j.revmed.2008.08.003 |
| الإتاحة: | https://doi.org/10.1016/j.revmed.2008.08.003Test https://www.hal.inserm.fr/inserm-00484589Test |
| رقم الانضمام: | edsbas.7A749B1 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.revmed.2008.08.003 |
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