التفاصيل البيبلوغرافية
| العنوان: |
Review © KSBMB & Springer-Verlag 2004 Functional Genomic Approaches Using the Nematode Caenorhabditis elegans as a Model System |
| المؤلفون: |
Junho Lee, Seunghee Nam, Soon Baek Hwang, Mingi Hong, Jae Young Kwon, Kyu Sang Joeng, Seol Hee Im, Jiwon Shim, Moon Cheol Park |
| المساهمون: |
The Pennsylvania State University CiteSeerX Archives |
| المصدر: |
http://bmbreports.org/jbmb/jbmb_filesTest/[37-1]0401271837_107-113.pdf. |
| سنة النشر: |
2003 |
| المجموعة: |
CiteSeerX |
| الوصف: |
Since the completion of the genome project of the nematode C. elegans in 1998, functional genomic approaches have been applied to elucidate the gene and protein networks in this model organism. The recent completion of the whole genome of C. briggsae, a close sister species of C. elegans, now makes it possible to employ the comparative genomic approaches for identifying regulatory mechanisms that are conserved in these species and to make more precise annotation of the predicted genes. RNA interference (RNAi) screenings in C. elegans have been performed to screen the whole genome for the genes whose mutations give rise to specific phenotypes of interest. RNAi screens can also be used to identify genes that act genetically together with a gene of interest. Microarray experiments have been very useful in |
| نوع الوثيقة: |
text |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| العلاقة: |
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.320.1201Test; http://bmbreports.org/jbmb/jbmb_filesTest/[37-1]0401271837_107-113.pdf |
| الإتاحة: |
http://bmbreports.org/jbmb/jbmb_filesTest/[37-1]0401271837_107-113.pdf |
| حقوق: |
Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
| رقم الانضمام: |
edsbas.7A6B7DB1 |
| قاعدة البيانات: |
BASE |
