دورية أكاديمية
Prognosis of PCI in AMI setting in the elderly population: outcomes from the multicenter prospective e‐ULTIMASTER registry
| العنوان: | Prognosis of PCI in AMI setting in the elderly population: outcomes from the multicenter prospective e‐ULTIMASTER registry |
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| المؤلفون: | Saada, Majdi, Kobo, Ofer, Polad, Jawed, Halabi, Majdi, IJsselmuiden, Alexander J. J., Puentes Rico, Angel Alberto, Monségu, Jacques, Austin, David, Baisebenov, Ruslan K., Spanó, Fabrizio, Roguin, Ariel |
| المصدر: | Clinical Cardiology |
| بيانات النشر: | Wiley |
| سنة النشر: | 2022 |
| المجموعة: | Universidad de Chile: Repositorio académico |
| مصطلحات موضوعية: | Age, Coronary artery disease, Elderly, Myocardial infarction, Outcome, Stent |
| الوصف: | Background Elderly patients with ST-elevation myocardial infarction (STEMI) who undergo percutaneous coronary intervention (PCI) are usually excluded from major trials. Hyopthesis This study sought to assess 1-year clinical outcomes following PCI with a drug-eluting stent in patients older than 80 years old with STEMI. Methods The large all-comer, multicontinental e-ULTIMASTER registry included 7507 patients with STEMI who underwent PCI using the Ultimaster stent. The primary clinical endpoint was 1-year target lesion failure, a composite of cardiac death (CD), target vessel-related myocardial infarction (TV-MI), or clinically driven target lesion revascularization (CD-TLR). Results There were 457 (6.1%) patients in the elderly group (>= 80 years old) that were compared to 7050 (93.9%) patients <80 years. The elderly patients included more female patients and had significantly more comorbidities and had more complex coronary anatomy. The primary endpoint occurred in 7.2% of the elderly, compared to 3.1% of the younger group (p < .001). All-cause mortality was significantly higher among the elderly group compared to the younger group (10.1% vs. 2.3%, p < .0001), as well as CD (6.1% vs. 1.6%, p < .0001), but not TV-MI (1.1% vs. 0.7%, p = .34) or CD-TLR (1.1% vs. 1.4%, p = .63). Conclusion Elderly patients with STEMI presentation had a higher incidence of the composite endpoint than younger patients. All-cause and CD were higher for elderly patients compared to patients younger than 80 years old. However, there was no difference in the incidence of TV-MI or target lesion revascularizations. These findings suggest that PCI for STEMI in elderly patients is relatively safe. ; Terumo Europe N.V. ; Versión publicada - versión final del editor |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | Clin Cardiol. 2022; 45: 1211–1219; https://repositorio.uchile.cl/handle/2250/194788Test |
| DOI: | 10.1002/clc.23902 |
| الإتاحة: | https://doi.org/10.1002/clc.23902Test https://repositorio.uchile.cl/handle/2250/194788Test |
| حقوق: | Attribution-NonCommercial-NoDerivs 3.0 United States ; http://creativecommons.org/licenses/by-nc-nd/3.0/usTest/ |
| رقم الانضمام: | edsbas.79B61079 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1002/clc.23902 |
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