دورية أكاديمية
Transforming growth factor-β activation in cell-free extracellular matrix preparations:Commentary
العنوان: | Transforming growth factor-β activation in cell-free extracellular matrix preparations:Commentary |
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المؤلفون: | Couchman, John R |
المصدر: | Couchman , J R 2019 , ' Transforming growth factor-β activation in cell-free extracellular matrix preparations : Commentary ' , Folia Histochemica et Cytobiologica , vol. 57 , no. 4 , pp. 157-158 . https://doi.org/10.5603/FHC.a2019.0017Test |
سنة النشر: | 2019 |
المجموعة: | University of Copenhagen: Research / Forskning ved Københavns Universitet |
مصطلحات موضوعية: | /dk/atira/pure/core/keywords/TheFacultyOfHealthScience, Faculty of Health and Medical Sciences |
الوصف: | Transforming growth factor-β (TGF-β) is an important regulator of many cellular and immunological functions. It is often deposited in extracellular matrices in a latent form. This commentary is to draw attention to the likelihood that preparing cell-free matrices from tissue cultures by high pH buffers, such as ammonium hydroxide, can activate the TGF-β. Therefore, cells subsequently seeded onto such matrices may respond to the presence of active TGF-β in addition to interactions with macromolecular extracellular matrix components. |
نوع الوثيقة: | article in journal/newspaper |
وصف الملف: | application/pdf |
اللغة: | English |
DOI: | 10.5603/FHC.a2019.0017 |
الإتاحة: | https://doi.org/10.5603/FHC.a2019.0017Test https://curis.ku.dk/portal/da/publications/transforming-growth-factor-activation-in-cellfree-extracellular-matrix-preparationsTest(d8eaa9c7-7e64-45f6-b2f4-591d784432bb).html https://curis.ku.dk/ws/files/234277818/66341_195919_2_PB.pdfTest |
حقوق: | info:eu-repo/semantics/openAccess |
رقم الانضمام: | edsbas.797CF72 |
قاعدة البيانات: | BASE |
DOI: | 10.5603/FHC.a2019.0017 |
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