دورية أكاديمية
Physiological Predictors of Weight Regain at 1-Year Follow-Up in Weight-Reduced Adults with Obesity
| العنوان: | Physiological Predictors of Weight Regain at 1-Year Follow-Up in Weight-Reduced Adults with Obesity |
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| المؤلفون: | Nymo, Siren, Coutinho, Silvia R, Rehfeld, Jens F, Truby, Helen, Kulseng, Bård, Martins, Catia |
| المصدر: | Nymo , S , Coutinho , S R , Rehfeld , J F , Truby , H , Kulseng , B & Martins , C 2019 , ' Physiological Predictors of Weight Regain at 1-Year Follow-Up in Weight-Reduced Adults with Obesity ' , Obesity , vol. 27 , no. 6 , pp. 925-931 . https://doi.org/10.1002/oby.22476Test |
| سنة النشر: | 2019 |
| المجموعة: | University of Copenhagen: Research / Forskning ved Københavns Universitet |
| الوصف: | OBJECTIVE: This study aimed to assess whether changes in resting metabolic rate (RMR), exercise-induced energy expenditure (EIEE), and appetite following weight loss (WL) are associated with weight regain at 1 year. METHODS: Thirty-six adults with obesity underwent 8 weeks of a very-low-energy diet, followed by 4 weeks of refeeding and a 1-year maintenance program. RMR, EIEE, appetite ratings, and active ghrelin, peptide YY, glucagon-like peptide-1, cholecystokinin, and insulin concentrations were measured at baseline, week 13, and 1 year. RESULTS: A 17% WL (-20 ± 5 kg [mean ± SD]; range: -11.7 to -32.2 kg; P < 0.001) was achieved at week 13. After 1 year, weight regain was 2.5 ± 9.0 kg (not significant), ranging from -18.2 to 22.5 kg. Both fat mass and fat-free mass were reduced at week 13 (-17.9 ± 4.8 and -2.9 ± 2.7 kg, respectively; P < 0.001), while only loss of fat mass was sustained at 1 year. WL was associated with reduced RMR, EIEE, and fasting/postprandial insulin (all P < 0.001), as well as increased fasting hunger (P < 0.01) and fasting/postprandial active ghrelin (P < 0.001). There were no significant correlations between changes in RMR, EIEE, or appetite with WL and weight regain at 1 year. CONCLUSIONS: No clear evidence emerged that changes in RMR, EIEE, or appetite following WL can predict weight regain at 1 year, but larger studies are needed to confirm these results. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| DOI: | 10.1002/oby.22476 |
| الإتاحة: | https://doi.org/10.1002/oby.22476Test https://curis.ku.dk/portal/da/publications/physiological-predictors-of-weight-regain-at-1year-followup-in-weightreduced-adults-with-obesityTest(0f1df27e-f30c-4df8-82c5-8a80f020f077).html https://curis.ku.dk/ws/files/224387685/Nymo_et_al_2019_Obesity.pdfTest |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.78A5718F |
| قاعدة البيانات: | BASE |
| DOI: | 10.1002/oby.22476 |
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