دورية أكاديمية
Comparison of global myocardial strain assessed by cardiovascular magnetic resonance tagging and feature tracking to infarct size at predicting remodelling following STEMI.
| العنوان: | Comparison of global myocardial strain assessed by cardiovascular magnetic resonance tagging and feature tracking to infarct size at predicting remodelling following STEMI. |
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| المؤلفون: | Shetye, Abhishek M., Nazir, Sheraz A., Razvi, Naveed A., Price, Nathan, Khan, Jamal N., Lai, Florence Y., Squire, Iain B., McCann, Gerald P., Arnold, Jayanth R. |
| بيانات النشر: | BioMed Central |
| سنة النشر: | 2017 |
| المجموعة: | University of Leicester: Leicester Research Archive (LRA) |
| مصطلحات موضوعية: | Cardiac magnetic resonance, Feature tracking, Remodelling, ST-elevation myocardial infarction, Strain, Tagging |
| الوصف: | All data generated or analysed during this study are included in this published article. Raw data for the study is stored and archived and is available upon request. ; BACKGROUND: To determine if global strain parameters measured by cardiovascular magnetic resonance (CMR) acutely following ST-segment Elevation Myocardial Infarction (STEMI) predict adverse left ventricular (LV) remodelling independent of infarct size (IS). METHODS: Sixty-five patients with acute STEMI (mean age 60 ± 11 years) underwent CMR at 1-3 days post-reperfusion (baseline) and at 4 months. Global peak systolic circumferential strain (GCS), measured by tagging and Feature Tracking (FT), and global peak systolic longitudinal strain (GLS), measured by FT, were calculated at baseline, along with IS. On follow up scans, volumetric analysis was performed to determine the development of adverse remodelling - a composite score based on development of either end-diastolic volume index [EDVI] ≥20% or end-systolic volume index [ESVI] ≥15% at follow-up compared to baseline. RESULTS: The magnitude of GCS was higher when measured using FT (-21.1 ± 6.3%) than with tagging (-12.1 ± 4.3; p < 0.001 for difference). There was good correlation of strain with baseline LVEF (r 0.64-to 0.71) and IS (ρ -0.62 to-0.72). Baseline strain parameters were unable to predict development of adverse LV remodelling. Only baseline IS predicted adverse remodelling - Odds Ratio 1.05 (95% CI 1.01-1.10, p = 0.03), area under the ROC curve 0.70 (95% CI 0.52-0.87, p = 0.04). CONCLUSION: Baseline global strain by CMR does not predict the development of adverse LV remodelling following STEMI. ; British Heart Foundation (BHF), National Institute for Health Research (NIHR), and the University of Leicester, United Kingdom. This work is part of a student (AS) Bachelor of Science project funded by the University of Leicester and the NIHR (GPM is supported by a NIHR Postdoctoral Research Fellowship). All patients were recruited as part of a previous project grant funded by the BHF ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1471-2261 |
| العلاقة: | http://www.ncbi.nlm.nih.gov/pubmed/28056808Test; BMC Cardiovascular Disorders, 2017, 17 (1); http://bmccardiovascdisord.biomedcentral.com/articles/10.1186/s12872-016-0461-6Test; http://hdl.handle.net/2381/39427Test |
| DOI: | 10.1186/s12872-016-0461-6 |
| الإتاحة: | https://doi.org/10.1186/s12872-016-0461-6Test http://hdl.handle.net/2381/39427Test |
| حقوق: | This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0Test/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0Test/) applies to the data made available in this article, unless otherwise stated. |
| رقم الانضمام: | edsbas.77C86F0B |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 14712261 |
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| DOI: | 10.1186/s12872-016-0461-6 |