التفاصيل البيبلوغرافية
| العنوان: |
Low incidence of acute kidney injury in VLBW infants with restrictive use of mechanical ventilation |
| المؤلفون: |
Burgmaier, Kathrin, Zeiher, Melanie, Weber, Anna, Cosgun, Zülfü C., Aydin, Aynur, Kuehne, Benjamin, Burgmaier, Mathias, Hellmich, Martin, Mehler, Katrin, Kribs, Angela, Habbig, Sandra |
| المساهمون: |
Universitätsklinikum Köln |
| المصدر: |
Pediatric Nephrology ; ISSN 0931-041X 1432-198X |
| بيانات النشر: |
Springer Science and Business Media LLC |
| سنة النشر: |
2023 |
| مصطلحات موضوعية: |
Nephrology, Pediatrics, Perinatology and Child Health |
| الوصف: |
Background We assessed the incidence of and risk factors for acute kidney injury (AKI) in very low birthweight infants (VLBW) in a center with a specific neonatal management protocol focusing on avoidance of early mechanical ventilation (MV). Methods This retrospective single center analysis includes 128 infants born in 2020 with a gestational age ≥ 22 weeks who were screened for AKI using the nKDIGO criteria. Results AKI was identified in 25/128 patients (19.5%) with eight of them (6.3%) presenting with severe AKI. Low gestational age, birthweight and 10-minute Apgar score as well as high CRIB-1 score were all associated with incidence of AKI. Forty-five percent of the infants with MV developed AKI vs. 8.9% of those without MV ( p < 0.001). Early onset of MV and administration of more than 3 dosages of NSAIDs for patent duct were identified as independent risk factors for AKI in a logistic regression analysis. Conclusions We report a substantially lower frequency of AKI in VLBW infants as compared to previous studies, along with a very low rate of MV. A neonatal protocol focusing on avoidance of MV within the first days of life may be a key factor to decrease the risk of AKI in immature infants. Graphical abstract |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| DOI: |
10.1007/s00467-023-06182-8 |
| DOI: |
10.1007/s00467-023-06182-8.pdf |
| DOI: |
10.1007/s00467-023-06182-8/fulltext.html |
| الإتاحة: |
https://doi.org/10.1007/s00467-023-06182-8Test |
| حقوق: |
https://creativecommons.org/licenses/by/4.0Test ; https://creativecommons.org/licenses/by/4.0Test |
| رقم الانضمام: |
edsbas.77BF9853 |
| قاعدة البيانات: |
BASE |
