دورية أكاديمية
Quantitative resistance to clubroot infection mediated by transgenerational epigenetic variation in Arabidopsis
| العنوان: | Quantitative resistance to clubroot infection mediated by transgenerational epigenetic variation in Arabidopsis |
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| المؤلفون: | Liegard, Benjamin, Baillet, Victoire, Etcheverry, Mathilde, Joseph, Evens, Lariagon, Christine, Lemoine, Jocelyne, Evrard, Aurélie, Colot, Vincent, Gravot, Antoine, Manzanares-Dauleux, Maria, M., Jubault, Mélanie |
| المساهمون: | Institut de Génétique, Environnement et Protection des Plantes (IGEPP), Institut National de la Recherche Agronomique (INRA)-Université de Rennes (UR)-AGROCAMPUS OUEST, Institut de biologie de l'ENS Paris (IBENS), Département de Biologie - ENS Paris, École normale supérieure - Paris (ENS-PSL), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS-PSL), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), This research was supported by AGROCAMPUS OUEST, INRA and Université de Rennes. Benjamin Liégard was a PhD student co-funded by INRA BAP department and Brittany Region. |
| المصدر: | ISSN: 0028-646X. |
| بيانات النشر: | HAL CCSD Wiley |
| سنة النشر: | 2019 |
| المجموعة: | Université de Rennes 1: Publications scientifiques (HAL) |
| مصطلحات موضوعية: | quantitative resistance, Plasmodiophora brassicae, methylome, EpiRIL, epigenet- ics, clubroot, Arabidopsis, transgenerational, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], [SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], [SDV.BV]Life Sciences [q-bio]/Vegetal Biology, [SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE], [SDV.GEN.GPL]Life Sciences [q-bio]/Genetics/Plants genetics, [SDV.GEN.GPO]Life Sciences [q-bio]/Genetics/Populations and Evolution [q-bio.PE] |
| الوصف: | International audience ; Quantitative disease resistance, often influenced by environmental factors, is thought to be the result of DNA sequence variants segregating at multiple loci. However, heritable differences in DNA methylation, so-called transgenerational epigenetic variants, also could contribute to quantitative traits. Here, we tested this possibility using the well-characterized quantitative resistance of Arabidopsis to clubroot, a Brassica major disease caused by Plasmodiophora brassicae. For that, we used the epigenetic recombinant inbred lines (epiRIL) derived from the cross ddm1-2 9 Col-0, which show extensive epigenetic variation but limited DNA sequence variation. Quantitative loci under epigenetic control (QTL epi) mapping was carried out on 123 epiRIL infected with P. brassicae and using various disease-related traits. EpiRIL displayed a wide range of continuous phenotypic responses. Twenty QTL epi were detected across the five chromosomes, with a bona fide epigenetic origin for 16 of them. The effect of five QTL epi was dependent on temperature conditions. Six QTL epi co-localized with previously identified clubroot resistance genes and QTL in Arabidopsis. Co-localization of clubroot resistance QTL epi with previously detected DNA-based QTL reveals a complex model in which a combination of allelic and epiallelic variations interacts with the environment to lead to variation in clubroot quantitative resistance. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| ردمك: | 978-0-00-459928-1 0-00-459928-4 |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/30393890; hal-02414174; https://hal.science/hal-02414174Test; https://hal.science/hal-02414174/documentTest; https://hal.science/hal-02414174/file/nph.15579.pdfTest; PRODINRA: 466662; PUBMED: 30393890; PUBMEDCENTRAL: PMC6587750; WOS: 000459928400040 |
| DOI: | 10.1111/nph.15579 |
| الإتاحة: | https://doi.org/10.1111/nph.15579Test https://hal.science/hal-02414174Test https://hal.science/hal-02414174/documentTest https://hal.science/hal-02414174/file/nph.15579.pdfTest |
| حقوق: | info:eu-repo/semantics/OpenAccess |
| رقم الانضمام: | edsbas.774C6118 |
| قاعدة البيانات: | BASE |
| ردمك: | 9780004599281 0004599284 |
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| DOI: | 10.1111/nph.15579 |