دورية أكاديمية
Effect of the sterol demethylation-inhibiting fungicide fenarimol on selected biochemical parameters in rats
| العنوان: | Effect of the sterol demethylation-inhibiting fungicide fenarimol on selected biochemical parameters in rats |
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| المساهمون: | Uludağ Üniversitesi/Fen-Edebiyat Fakültesi/Biyoloji Bölümü., orcid:0000-0002-6729-7908, Arı, Ferda, Dere, Egemen, AAH-5068-2021, AAG-7012-2021, 24376085300, 6603627015 |
| بيانات النشر: | Sciendo |
| سنة النشر: | 2010 |
| المجموعة: | Açık Erişim@BUU (Bursa Uludağ Üniversitesi) |
| مصطلحات موضوعية: | Fenarimol, Lactate dehydrogenase, Alkaline phosphatase, Alanine amino transferase, Aspartate amino transferase, Induced infertility, Aromatase-activity, Pesticides, Induction, Mechanism, Enzymes, System, Alpha, Liver, Veterinary sciences, Rattus, Sango, Sprouts (Food), Juices |
| الوصف: | Fenarimol, a 2,4'-dichloro-alpha-(pyrimidin-5-yl) benzhydryl alcohol fungicide and steroid demethylation inhibitor, has been reported to affect the actions of multiple CYP450 isoforms, including key enzymes. The aim of this study was to evaluate the effects of fenarimol on a set of biochemical parameters in rats. Rats were intraperitoneally injected with a 200 mg kg(-1) dose of fenarimol. Blood samples were collected for measurements of serum alkaline phosphatase (ALP), alanine amino transferase (ALT), aspartate amino transferase (AST), creatine kinase (CK) activity, and levels of glucose, urea, sodium, and potassium. Serum was analysed at 0, 2, 4, 8, 16, 32, 64 and 72 h following injection. Our results demonstrated a statistically significant increase in ALP; ALT, AST, CK activities and levels of urea from time to time (p<0.05). Our results demonstrate that treatments with fenarimol can alter the activity and levels of selected serum enzymes and biochemical parameters in rats. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 0567-8315 1820-7448 |
| العلاقة: | Makale - Uluslararası Hakemli Dergi; BAP; Acta Veterinaria, Beograd; Arı, F. ve Dere, E. (2010). "Effect of the sterol demethylation-inhibiting fungicide fenarimol on selected biochemical parameters in rats". Acta Veterinaria,Beograd 60(1), 31-38.; https://doi.org/10.2298/AVB1001031ATest; http://hdl.handle.net/11452/24501Test; 000276046300004; 2-s2.0-77950675400; 31; 38; 60 |
| DOI: | 10.2298/AVB1001031A |
| الإتاحة: | https://doi.org/10.2298/AVB1001031ATest http://hdl.handle.net/11452/24501Test |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.76E8184D |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 05678315 18207448 |
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| DOI: | 10.2298/AVB1001031A |