دورية أكاديمية
Potential celiac disease in type 1 diabetes: a multicenter study.
| العنوان: | Potential celiac disease in type 1 diabetes: a multicenter study. |
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| المؤلفون: | FRANZESE, ADRIANA, D. Iafusco, R. Spadaro, O. Cavaliere, F. Prisco, AURICCHIO, RENATA, TRONCONE, RICCARDO, G. Valerio, S. o. Diabetes, Diabetology |
| المساهمون: | Franzese, Adriana, D., Iafusco, R., Spadaro, O., Cavaliere, F., Prisco, Auricchio, Renata, Troncone, Riccardo, G., Valerio, S. o., Diabete, Diabetology |
| سنة النشر: | 2011 |
| المجموعة: | IRIS Università degli Studi di Napoli Federico II |
| مصطلحات موضوعية: | Adolescent, Celiac Disease, epidemiology/etiology, Child, Preschool, Cross-Sectional Studies, Diabetes Mellitu, Type 1, complications/epidemiology, Diet, Gluten-Free, Female, Humans, Infant, Male |
| الوصف: | To describe the prevalence of potential celiac disease (pot-CD) in young patients with type 1 diabetes mellitus (T1DM) and characterize their clinical features.This cross-sectional multicenter study involved 8717 T1DM patients from 31 Italian centers. Information was collected on the total number of T1DM patients, CD patients and pot-CD patients. The following data were collected on pot-CD patients: gender, age at T1DM diagnosis, age at the first CD serological positivity, presence of CD-related symptoms, presence of other autoimmune disorders and treatment with gluten free diet (GFD). One thousand-three-hundred-sixty-one patients who were positive for CD serology were the control group.CD serological positivity was found in 7.2\% T1DM patients. Prevalence of pot-CD was 12.2\% (n=77) among CD positive patients: symptoms were present in 12/77; a third autoimmune disorder was found in 15 patients. Prevalence of pot-CD in the control population was 8.4\% (n=114; p=0.005). No difference was found with regard to clinical features. Only few symptomatic patients were on GFD both in T1DM and control patients.A higher prevalence of pot-CD was found in T1DM patients, that may be ascribed to the routine screening, although the influence of genetic factors cannot be excluded. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/wos/WOS:000289558300016; volume:92; firstpage:53; lastpage:56; numberofpages:3; journal:DIABETES RESEARCH AND CLINICAL PRACTICE; http://hdl.handle.net/11588/483736Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-79954568841; http://dx.doi.org/10.1016/j.diabres.2010.12.028Test |
| DOI: | 10.1016/j.diabres.2010.12.028 |
| الإتاحة: | https://doi.org/10.1016/j.diabres.2010.12.028Test http://hdl.handle.net/11588/483736Test |
| رقم الانضمام: | edsbas.76DD28DA |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.diabres.2010.12.028 |
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