دورية أكاديمية
The relationship between genetic liability, childhood maltreatment, and IQ: findings from the EU-GEI multicentric case–control study
| العنوان: | The relationship between genetic liability, childhood maltreatment, and IQ: findings from the EU-GEI multicentric case–control study |
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| المؤلفون: | Sideli, Lucia, Aas, Monica, Quattrone, Diego, La Barbera, Daniele, La Cascia, Caterina, Ferraro, Laura, Alameda, Luis, Velthorst, Eva, Trotta, Giulia, Tripoli, Giada, Schimmenti, Adriano, Fontana, Andrea, Gayer-Anderson, Charlotte, Stilo, Simona, Seminerio, Fabio, Sartorio, Crocettarachele, Marrazzo, Giovanna, Lasalvia, Antonio, Tosato, Sarah, Tarricone, Ilaria, Berardi, Domenico, D’andrea, Giuseppe, Arango, Celso, Arrojo, Manuel, Bernardo, Miguel, Bobes, Julio, Sanjuán, Julio, Santos, Jose, Luis, Menezes, Paulo, Rossi, Del-Ben, Cristina, Marta, Jongsma, Hannah, E, Jones, Peter, B, Kirkbride, James, B, Llorca, Pierre-Michel, Tortelli, Andrea, Pignon, Baptiste, de Haan, Lieuwe, Selten, Jean-Paul, van Os, Jim, Rutten, Bart, P, Bentall, Richard, Di Forti, Marta, Murray, Robin, M, Morgan, Craig, Fisher, Helen, L |
| المساهمون: | Università degli studi di Palermo - University of Palermo, King‘s College London, LUMSA University - Libera Università Maria SS. Assunta Rome, Italy (LUMSA), University of Oslo (UiO), Oslo University Hospital Oslo, Oslo Metropolitan University (OsloMet), Norwegian Centre for Mental Disorders Research Oslo (NORMENT), University of Oslo (UiO)-Haukeland University Hospital, University of Bergen (UiB)-University of Bergen (UiB)-Oslo University Hospital Oslo, Institute of Psychiatry, Psychology & Neuroscience, King's College London, Centro de Investigación Biomédica en Red Salud Mental Madrid (CIBER-SAM), Hospital Universitario Virgen del Rocío Sevilla, Universidad de Sevilla = University of Seville, Centre Hospitalier Universitaire Vaudois = Lausanne University Hospital Lausanne (CHUV), Instituto de Biomedicina de Sevilla Sevilla, Spain (IBIS/HUVR), Consejo Superior de Investigaciones Cientificas España = Spanish National Research Council Spain (CSIC)-Universidad de Sevilla = University of Seville, Mental Health Service Organization - GGZ Noord-Holland-Noord Hoorn, Netherlands (GGZ NHN), Università degli Studi di Enna " KORE " = Kore University of Enna, Institute of Psychiatry, Psychology, and Neuroscience, Università degli studi di Verona = University of Verona (UNIVR), Alma Mater Studiorum Università di Bologna = University of Bologna (UNIBO), Hospital General Universitario "Gregorio Marañón" Madrid, Universidad Complutense de Madrid = Complutense University of Madrid Madrid (UCM), Instituto de Investigación Sanitaria de Santiago de Compostela / Health Research Institute of Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago de Compostela Saint-Jacques-de-Compostelle, Espagne (CHUS), Universitat de Barcelona (UB), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Instituto de Salud Carlos III Madrid (ISC), Universidad de Oviedo Oviedo, Institute for Health Research of the Principality of Asturias Oviedo,Spain (ISPA), Universitat de València (UV), Hospital Virgen de La Luz Cuenca, Spain (HVDL), Universidade de São Paulo = University of São Paulo (USP), University College of London London (UCL), University of Cambridge UK (CAM), Cambridgeshire & Peterborough NHS Foundation Trust Cambridge (CPFT), Neuro-Psycho Pharmacologie des Systèmes Dopimanégiques sous-corticaux (NPsy-Sydo), CHU Clermont-Ferrand-Université d'Auvergne - Clermont-Ferrand I (UdA), Hôpital Maison Blanche, IMRB - "Neuropsychiatrie translationnelle" Créteil (U955 Inserm - UPEC), Institut Mondor de Recherche Biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Hôpital Henri Mondor, Fondation FondaMental Créteil, Amsterdam UMC - Amsterdam University Medical Center, Maastricht University Medical Centre (MUMC), Maastricht University Maastricht, University Medical Center Utrecht, University of Sheffield Sheffield, EU-GEI WP2 Group: Silvia Amoretti, Álvaro Andreu-Bernabeu, Grégoire Baudin, Stephanie Beards, Chiara Bonetto, Elena Bonora, Bibiana Cabrera, Angel Carracedo, Thomas Charpeaud, Javier Costas, Doriana Cristofalo, Pedro Cuadrado, Manuel Durán-Cutilla, Aziz Ferchiou, David Fraguas, Nathalie Franke, Flora Frijda, Paz Garcia-Portilla, Javier González Peñas, Kathryn Hubbard, Stéphane Jamain, Estela Jiménez-López, Marion Leboyer, Cloe Llorente, Gonzalo López Montoya, Esther Lorente-Rovira, Covadonga M Díaz-Caneja, Camila Marcelino Loureiro, Mario Matteis, Elles Messchaart, Ma Dolores Moltó, Gisela Mezquida, Carmen Moreno, Roberto Muratori, Juan Nacher, Mara Parellada, Marta Rapado-Castro, Mirella Ruggeri, Jean-Romain Richard, José Juan Rodríguez Solano, Pilar A Sáiz, Teresa Sánchez-Gutierrez, Emilio Sánchez, Franck Schürhoff, Marco Seri, Rosana Shuhama, Fabian Termorshuizen, Anne-Marie Tronche, Daniella van Dam, Elsje van der Ven |
| المصدر: | ISSN: 0933-7954. |
| بيانات النشر: | HAL CCSD Springer Verlag |
| سنة النشر: | 2023 |
| المجموعة: | HAL Clermont Auvergne (Université Blaise Pascal Clermont-Ferrand / Université d'Auvergne) |
| مصطلحات موضوعية: | Childhood adversity, Cognition, Family history of psychosis, First episode, Polygenic risk score, Psychosis, [SDV]Life Sciences [q-bio] |
| الوصف: | International audience ; This study investigated if the association between childhood maltreatment and cognition among psychosis patients and community controls was partially accounted for by genetic liability for psychosis. Patients with first-episode psychosis (N = 755) and unaffected controls (N = 1219) from the EU-GEI study were assessed for childhood maltreatment, intelligence quotient (IQ), family history of psychosis (FH), and polygenic risk score for schizophrenia (SZ-PRS). Controlling for FH and SZ-PRS did not attenuate the association between childhood maltreatment and IQ in cases or controls. Findings suggest that these expressions of genetic liability cannot account for the lower levels of cognition found among adults maltreated in childhood. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/37335320; inserm-04197570; https://inserm.hal.science/inserm-04197570Test; https://inserm.hal.science/inserm-04197570/documentTest; https://inserm.hal.science/inserm-04197570/file/s00127-023-02513-0.pdfTest; PUBMED: 37335320; PUBMEDCENTRAL: PMC10460355 |
| DOI: | 10.1007/s00127-023-02513-0 |
| الإتاحة: | https://doi.org/10.1007/s00127-023-02513-0Test https://inserm.hal.science/inserm-04197570Test https://inserm.hal.science/inserm-04197570/documentTest https://inserm.hal.science/inserm-04197570/file/s00127-023-02513-0.pdfTest |
| حقوق: | info:eu-repo/semantics/OpenAccess |
| رقم الانضمام: | edsbas.7427E839 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1007/s00127-023-02513-0 |
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