دورية أكاديمية
NECROSING GASTROENTEROCOLITIS IN NEWBORN PATIENTS: CLINICAL EVALUATION AND POSSIBLE TREATMENTS ; GASTROENTEROCOLITE NECROSANTE EM PACIENTES RECÉM-NASCIDOS: AVALIAÇÃO CLÍNICA E POSSÍVEIS TRATAMENTOS
| العنوان: | NECROSING GASTROENTEROCOLITIS IN NEWBORN PATIENTS: CLINICAL EVALUATION AND POSSIBLE TREATMENTS ; GASTROENTEROCOLITE NECROSANTE EM PACIENTES RECÉM-NASCIDOS: AVALIAÇÃO CLÍNICA E POSSÍVEIS TRATAMENTOS |
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| المؤلفون: | Sousa, Daniela de Melo, Nunes, Ana Laura Horta, Santos, Luiza Monteiro dos, Pereira, Clara Pedrosa, Almeida, Ana Beatriz Lima de |
| المصدر: | Revista Ibero-Americana de Humanidades, Ciências e Educação; Vol. 9 No. 9 (2023): Revista Ibero-Americana de Humanidades, Ciências e Educação- REASE ; 820- 832 ; Revista Ibero-Americana de Humanidades, Ciências e Educação; v. 9 n. 9 (2023): Revista Ibero-Americana de Humanidades, Ciências e Educação- REASE ; 2675-3375 ; 10.51891/rease.v9i9 |
| بيانات النشر: | Revista Ibero-Americana de Humanidades, Ciências e Educação |
| سنة النشر: | 2023 |
| مصطلحات موضوعية: | Necrotizing enterocolitis. Neonates. Diagnosis. Treatment. Result, Enterocolite necrosante. Neonatos. Diagnóstico. Tratamento. Resultado |
| الوصف: | Necrotizing gastroenterocolitis (GECN) is a serious inflammatory disease that affects the gastrointestinal tract of newborns, especially premature babies, and can lead to intestinal necrosis and perforation. GECN is a leading cause of neonatal morbidity and mortality, with an estimated incidence of 0.3 to 2.4 cases per 1000 live births and a mortality rate of 15 to 30%. Treatment for GECN depends on the stage of the disease and may include supportive measures, antibiotic therapy, parenteral nutrition and surgery. Objective: to synthesize scientific evidence on the clinical assessment and possible treatments of GECN in newborn patients. Methodology: This review was carried out in accordance with the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) protocol. The PubMed, Scielo, Web of Science and Cochrane Library databases were consulted, using the following descriptors: “necrotizing enterocolitis”, “neonates”, “diagnosis”, “treatment” and “outcome”. Articles published in the last 10 years (2013-2023), in Portuguese or English, that addressed clinical, diagnostic, therapeutic or prognostic aspects of GECN in newborns were included. Articles that were not original, that did not have sufficient data or that were not relevant to the topic were excluded. The selected articles were evaluated regarding methodological quality, data extraction and analysis of results. Results: 16 articles were selected. The diagnosis of GECN was based on the combination of clinical signs (abdominal distension, bilious vomiting, blood in the stool), laboratory changes (leukocytosis or leukopenia, metabolic acidosis, thrombocytopenia) and radiological findings (intestinal pneumatosis, pneumoperitoneum). Treatment for GECN varied according to the stage of the disease and consisted of supportive measures (fasting, hydration, oxygenation, monitoring), antibiotic therapy (ampicillin, gentamicin, metronidazole), parenteral nutrition and surgery (laparotomy, enterostomy, intestinal resection). The main complications of ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | Portuguese |
| العلاقة: | https://periodicorease.pro.br/rease/article/view/11241/4916Test; https://periodicorease.pro.br/rease/article/view/11241Test |
| DOI: | 10.51891/rease.v9i9.11241 |
| الإتاحة: | https://doi.org/10.51891/rease.v9i9.11241Test https://doi.org/10.51891/rease.v9i9Test https://periodicorease.pro.br/rease/article/view/11241Test |
| حقوق: | Copyright (c) 2023 Revista Ibero-Americana de Humanidades, Ciências e Educação |
| رقم الانضمام: | edsbas.73BC09E |
| قاعدة البيانات: | BASE |
| DOI: | 10.51891/rease.v9i9.11241 |
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