دورية أكاديمية
Effects of ischemic postconditioning and long non-coding RNAs in ischemic stroke
| العنوان: | Effects of ischemic postconditioning and long non-coding RNAs in ischemic stroke |
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| المؤلفون: | Wei Ma, Kewei Zhu, Luwei Yin, Jinwei Yang, Jinfen Zhang, Hongjie Wu, Kuangpin Liu, Chunyan Li, Wei Liu, Jianhui Guo, Liyan Li |
| المصدر: | Bioengineered, Vol 13, Iss 6, Pp 14799-14814 (2022) |
| بيانات النشر: | Taylor & Francis Group |
| سنة النشر: | 2022 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | Ischemic stroke, ischemic postconditioning, remote ischemic postconditioning, long non-coding RNAs, neuroprotective effect, Biotechnology, TP248.13-248.65 |
| الوصف: | Stroke is a main cause of disability and death among adults in China, and acute ischemic stroke accounts for 80% of cases. The key to ischemic stroke treatment is to recanalize the blocked blood vessels. However, more than 90% of patients cannot receive effective treatment within an appropriate time, and delayed recanalization of blood vessels causes reperfusion injury. Recent research has revealed that ischemic postconditioning has a neuroprotective effect on the brain, but the mechanism has not been fully clarified. Long non-coding RNAs (lncRNAs) have previously been associated with ischemic reperfusion injury in ischemic stroke. LncRNAs regulate important cellular and molecular events through a variety of mechanisms, but a comprehensive analysis of potential lncRNAs involved in the brain protection produced by ischemic postconditioning has not been conducted. In this review, we summarize the common mechanisms of cerebral injury in ischemic stroke and the effect of ischemic postconditioning, and we describe the potential mechanisms of some lncRNAs associated with ischemic stroke. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 2165-5987 2165-5979 |
| العلاقة: | https://doaj.org/toc/2165-5979Test; https://doaj.org/toc/2165-5987Test; https://doaj.org/article/f80b760fd8d64c09b35729a5157b5013Test |
| DOI: | 10.1080/21655979.2022.2108266 |
| الإتاحة: | https://doi.org/10.1080/21655979.2022.2108266Test https://doaj.org/article/f80b760fd8d64c09b35729a5157b5013Test |
| رقم الانضمام: | edsbas.73B248E |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 21655987 21655979 |
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| DOI: | 10.1080/21655979.2022.2108266 |