دورية أكاديمية
Histopathological characterization of the oral lichenoid disease subtypes and the relation with the clinical data
| العنوان: | Histopathological characterization of the oral lichenoid disease subtypes and the relation with the clinical data |
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| المؤلفون: | Alberdi-Navarro, Javier, Marichalar-Mendia, Xabier, Lartitegui-Sebastian, Maria Jose, Gainza-Cirauqui, Maria Luisa, Echebarria-Goikouria, Maria-Angeles, Aguirre-Urizar, Jose Manuel |
| بيانات النشر: | Medicina Oral Sl |
| سنة النشر: | 2017 |
| المجموعة: | University of Malta: OAR@UM / L-Università ta' Malta |
| مصطلحات موضوعية: | Lichen Planus, Oral, Histology, Pathological, Mouth -- Diseases -- Diagnosis, Dentistry, Oral medicine, Precancerous conditions |
| الوصف: | Background: The aim of the study was to analyze the histopathological characteristics of samples with a diagnosis of oral lichenoid disease (OLD) and their link with the location and the type of clinical lesion, and the clinicopathological subtypes. ; Material and methods: Retrospective study on 85 consecutive patients diagnosed with OLD (58 women and 27 men, mean age of 57.7 years). Clinical and histopathological characterization of each case (modified WHO criteria). Collection of the clinical and histopathological data of the lesions. Descriptive and comparative statistical analysis of the results. ; Results: The 78.8% of the cases were considered clinically typical while the 21.2% were considered compatible. Histologically, 52.9% were classified as typical and 47.1% as compatible. Biopsies from "plaque-like" lesions presented hyperkeratosis (p>0.001) and epithelial dysplasia (p=0.06) more frequently. Furthermore, acute inflammation was more evident in erosive-ulcerative lesions (p=0.001). Differences regarding the location of the biopsy were statistically non-significant. However, 42.9% of the tongue biopsies showed epithelial dysplasia. ; Conclusions: The histopathological aspect of this disorder is not specific and does not allow us to differentiate between the main subtypes. Therefore, the main reasons to perform a biopsy in this disorder are to define the differential diagnosis and to rule out epithelial dysplasia or a carcinoma. The final histopathological result may be subject to the type of lesion that is biopsied. ; peer-reviewed |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | Alberdi-Navarro, J., Marichalar-Mendia, X., Lartitegui-Sebastián, M. J., Gainza-Cirauqui, M. L., Echebarria-Goikouria, M. Á., & Aguirre-Urizar, J. M. (2017). Histopathological characterization of the oral lichenoid disease subtypes and the relation with the clinical data. Medicina Oral, Patologia Oral y Cirugia Bucal, 22(3), e307.; https://www.um.edu.mt/library/oar/handle/123456789/91439Test |
| DOI: | 10.4317/medoral.21730 |
| الإتاحة: | https://doi.org/10.4317/medoral.21730Test https://www.um.edu.mt/library/oar/handle/123456789/91439Test |
| حقوق: | info:eu-repo/semantics/openAccess ; The copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder. |
| رقم الانضمام: | edsbas.72A78DEA |
| قاعدة البيانات: | BASE |
| DOI: | 10.4317/medoral.21730 |
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