التفاصيل البيبلوغرافية
العنوان: |
The whitening efficacy of a compound formula examined using an ultraviolet‐induced skin melanization model |
المؤلفون: |
Shu, Xiaohong, Dong, Xin, Ma, Yuhong, Huo, Wei, Li, Zhaoxia, Zou, Lin, Tang, Ying, Li, Li, Wang, Xi |
المصدر: |
Journal of Cosmetic Dermatology ; ISSN 1473-2130 1473-2165 |
بيانات النشر: |
Wiley |
سنة النشر: |
2024 |
المجموعة: |
Wiley Online Library (Open Access Articles via Crossref) |
الوصف: |
Background In Eastern culture, a fair complexion is the standard of beauty, leading to appearance‐related distress among women with darker skin or facial pigmentation. Women seek whitening cosmetics to enhance their skin tone or correct their pigmentation, but their safety and effectiveness are paramount factors to consider. In this study, we evaluated the safety and whitening effects of a compound formula denoted as TEST comprising astaxanthin, nicotinamide, arbutin, and tranexamic acid. Methods Primary skin irritation and skin‐whitening efficacy were examined. Three qualified melanization areas were treated with TEST, 7% ascorbic acid, or a blank. Skin color, the individual type angle (ITA°), and the melanin index (MI) were compared among treatment areas. Results TEST did not induce a skin response and exhibited a significantly higher ITA° than the blank, while no significant difference was observed with that of 7% ascorbic acid. Furthermore, the MI of TEST was significantly reduced posttreatment. Conclusions TEST could be integrated into spot‐fading and skin‐whitening cosmeceuticals or functional cosmetics. |
نوع الوثيقة: |
article in journal/newspaper |
اللغة: |
English |
DOI: |
10.1111/jocd.16332 |
الإتاحة: |
https://doi.org/10.1111/jocd.16332Test |
حقوق: |
http://creativecommons.org/licenses/by/4.0Test/ |
رقم الانضمام: |
edsbas.72001D9A |
قاعدة البيانات: |
BASE |