التفاصيل البيبلوغرافية
| العنوان: |
Design and Discovery of MRTX0902, a Potent, Selective, Brain-Penetrant, and Orally Bioavailable Inhibitor of the SOS1:KRAS Protein–Protein Interaction |
| المؤلفون: |
Ketcham, John M., Haling, Jacob, Khare, Shilpi, Bowcut, Vickie, Briere, David M., Burns, Aaron C., Gunn, Robin J., Ivetac, Anthony, Kuehler, Jon, Kulyk, Svitlana, Laguer, Jade, Lawson, J. David, Moya, Krystal, Nguyen, Natalie, Rahbaek, Lisa, Saechao, Barbara, Smith, Christopher R., Sudhakar, Niranjan, Thomas, Nicole C., Vegar, Laura, Vanderpool, Darin, Wang, Xiaolun, Yan, Larry, Olson, Peter, Christensen, James G., Marx, Matthew A. |
| المساهمون: |
Mirati Therapeutics |
| المصدر: |
Journal of Medicinal Chemistry ; volume 65, issue 14, page 9678-9690 ; ISSN 0022-2623 1520-4804 |
| بيانات النشر: |
American Chemical Society (ACS) |
| سنة النشر: |
2022 |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| DOI: |
10.1021/acs.jmedchem.2c00741 |
| الإتاحة: |
https://doi.org/10.1021/acs.jmedchem.2c00741Test |
| حقوق: |
https://creativecommons.org/licenses/by/4.0Test/ |
| رقم الانضمام: |
edsbas.7183E640 |
| قاعدة البيانات: |
BASE |
