دورية أكاديمية

Primary Splenic Leiomyosarcoma in a Dog ; Avaliação clínico-patológica e imuno-histoquímica de um caso de leiomiossarcoma esplênico primário em cão

التفاصيل البيبلوغرافية
العنوان: Primary Splenic Leiomyosarcoma in a Dog ; Avaliação clínico-patológica e imuno-histoquímica de um caso de leiomiossarcoma esplênico primário em cão
المؤلفون: de Vargas Ritter, Larissa Eugênia, Pereira, Jaíne, Irgang, Andressa, Malvestio, Lygia Maria, Jacob Kolling, Giovani
المصدر: Acta Scientiae Veterinariae; Vol. 51 (2023): CASE REPORTS (SUPPLEMENT) ; Acta Scientiae Veterinariae; v. 51 (2023): CASE REPORTS (SUPPLEMENT) ; 1679-9216
بيانات النشر: Universidade Federal do Rio Grande do Sul
سنة النشر: 2024
المجموعة: SEER UFRGS (Universidade Federal do Rio Grande do Sul: Sistema Eletrônico de Editoração de Periódic)
مصطلحات موضوعية: baço, Imuno-histoquímica, músculo liso, neoplasia esplênica, tumores estromais
الوصف: Background: Leiomyosarcoma is a malignant mesenchymal neoplasm that commonly occurs in the uterus and gastrointestinal tract. Its primary occurrence in the spleen is considered rare, corresponding to only 4% of cases. The diagnosis must be made based on the patient’s medical history, clinical signs and complementary exams. The gold standard test for a definitive diagnosis is immunohistochemistry. This paper reports a case of one dog suffering from primary splenic leiomyosarcoma, emphasizing the importance of the immunohistochemical exam to conclude the diagnosis and select an ideal treatment. Case: A 10-year-old male Labrador dog, was treated after presenting for 4 days with hyporexia, constipation and sporadic cases of emesis. A physical examination of the patient revealed a body condition score of 9, with 1 being extremely thin and 9 being obese, abdominal pain during palpation, 5% dehydration, apathy and a slightly distended abdomen. Radiographic and ultrasound exams were requested to evaluate the thoracic and abdominal organs. In view of the results, the patient was referred to hospital for hydration, followed by a median celiotomy and orchiectomy. Blood count and serum biochemistry were requested as preoperative exams. In a laboratory evaluation, the animal’s blood count revealed normochromic normocytic anemia, thrombocytosis, high levels of total plasma protein and neutrophilia. The patient’s serum biochemistry profile indicated an increase in the enzyme activity of aminotransferase (AST), alkaline phosphatase (AP) and urea. An ultrasound exam revealed a 7.03 x 7.86 cm coarse-textured mass in the spleen. Right lateral view chest X-rays showed diaphragmatic compression by a round radiopaque structure projecting cranially, surpassing the 7th intercostal space, while the thoracic ventral-dorsal projection revealed absence of radiographic findings suggestive of pulmonary nodules or masses. The histopathological examination performed after total removal of the mass revealed moderately differentiated ...
نوع الوثيقة: article in journal/newspaper
وصف الملف: application/pdf
اللغة: English
العلاقة: https://seer.ufrgs.br/index.php/ActaScientiaeVeterinariae/article/view/132850/91031Test; https://seer.ufrgs.br/index.php/ActaScientiaeVeterinariae/article/view/132850Test
الإتاحة: https://seer.ufrgs.br/index.php/ActaScientiaeVeterinariae/article/view/132850Test
حقوق: Copyright (c) 2024 Larissa Eugênia de Vargas Ritter, Jaíne Pereira, Andressa Irgang, Lygia Maria Malvestio, Giovani Jacob Kolling ; http://creativecommons.org/licenses/by/4.0Test
رقم الانضمام: edsbas.70E8C6F3
قاعدة البيانات: BASE