التفاصيل البيبلوغرافية
| العنوان: |
The First Case of Laboratory-confirmed Dengue Virus Infection in Mimika, Papua Province, Indonesia |
| المؤلفون: |
Agustiningsih, A. (Agustiningsih), Ikawati, H. D. (Hartanti), Nugraha, A. A. (Arie), Setiawaty, V. (Vivi), Herman, R. (Reni) |
| المصدر: |
Health Science Journal of Indonesia |
| بيانات النشر: |
National Institute of Health Research and Development, Indonesian Ministry of Health |
| سنة النشر: |
2016 |
| المجموعة: |
neliti (Indonesia's Think Tank Database) |
| مصطلحات موضوعية: |
Indonesia, kabupaten Mimika, penentuan genotipe, penentuan serotipe, Mimika district, genotyping, serotyping, dengue |
| الوصف: |
Background: Dengue is the most important vector-borne disease that poses serious health problem both in tropical and subtropical countries. Since the first outbreak in Surabaya in 1968, dengue infection has spread in all provinces in Indonesia. Mimika district in Papua province, Indonesia, is a non-endemic dengue area with no laboratory-confirmed case reported. However, until 2012 there were 13 suspected dengue infection admitted to local General Hospital in Mimika district, Papua province, Indonesia. This study described the genetic characteristics of first laboratory-confirmed dengue virus (DENV) infection in Mimika district, Papua province, Indonesia. Methods: Viral isolation in C6/36 cell line, RT-PCR and serotyping were carried out to confirm the presence of DENV within serum patient of suspected DENV cases from Mimika district, Papua Province, Indonesia. Direct sequencing and phylogenetic analysis of complete coding sequence (CDS) of E gene was performed to the samples that have already confirmed positive DENV for viral genotyping. Results: Four cases were confirmed to be DENV by RT-PCR while only 2 samples were able to be culture in C6/36 mosquito cell line. Serotyping confirmed that the DENV from Mimika district, Papua province were DENV3 serotype. The genotyping showed that the DENV3 from Mimika district were belonged to genotype I. Conclusion: This study reported the first laboratory-confirmed of DENV cases in non-endemic dengue area, Mimika district, Papua Province, Indonesia. |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| العلاقة: |
https://www.neliti.com/publications/63102/the-first-case-of-laboratory-confirmed-dengue-virus-infection-in-mimika-papua-prTest |
| الإتاحة: |
https://www.neliti.com/publications/63102/the-first-case-of-laboratory-confirmed-dengue-virus-infection-in-mimika-papua-prTest |
| حقوق: |
(c) Health Science Journal of Indonesia, 2016 |
| رقم الانضمام: |
edsbas.6F96D40 |
| قاعدة البيانات: |
BASE |
