دورية أكاديمية
Trans-oral robotic surgery for the management of oropharyngeal carcinomas: a 9-year institutional experience
| العنوان: | Trans-oral robotic surgery for the management of oropharyngeal carcinomas: a 9-year institutional experience |
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| المؤلفون: | Meccariello G., Montevecchi F., D'Agostino G., Iannella G., Calpona S., Parisi E., Costantini M., Cammaroto G., Gobbi R., Firinu E., Sgarzani R., Nestola D., Bellini C., De Vito A., Amadori E., Vicini C. |
| المساهمون: | Meccariello, G., Montevecchi, F., D'Agostino, G., Iannella, G., Calpona, S., Parisi, E., Costantini, M., Cammaroto, G., Gobbi, R., Firinu, E., Sgarzani, R., Nestola, D., Bellini, C., De Vito, A., Amadori, E., Vicini, C. |
| بيانات النشر: | Pacini Editore S.p.A. |
| سنة النشر: | 2019 |
| المجموعة: | Sapienza Università di Roma: CINECA IRIS |
| مصطلحات موضوعية: | Cancer, Chemotherapy, HPV, Neck, Oropharyngeal, P16, Radiotherapy, Robotic surgery, Disease-Free Survival, Drug Therapy, Human, Margins of Excision, Multivariate Analysi, Neoplasm Staging, Oropharyngeal Neoplasm, Papillomavirus Infection, Regression Analysi, Retrospective Studie, Robotic Surgical Procedures |
| الوصف: | Trans-oral robotic surgery (TORS) has changed surgical management of patients with oropharyngeal squamous cell carcinomas (OPSCC). In this study we present surgical and oncologic outcomes of patients with oropharyngeal squamous cell carcinomas, treated using TORS, with and without an adjuvant therapy. Sixty patients with oropharyngeal squamous cell carcinomas treated with TORS between January 2008 and December 2017 have been retrospectively evaluated considering clinicopathologic features, disease characteristics, adjuvant treatments and oncological outcomes. TORS was performed for OPSCC to the base of tongue in 41.7%, tonsils in 46.7%, soft palate and posterior pharyngeal wall in 3.3% and 5%, respectively. Neck dissection was performed in 43.3% of patients. Management strategies included surgery alone in 30%, TORS and adjuvant radiotherapy in 33.3%, and TORS plus adjuvant chemotherapy in 36.7%. The 5-year overall survival of the total group was 77.6%, the 5-year disease-free survival rate was 85.2%, and the 5-year local recurrence-free survival rate was 90.6%. Finally, in selected patients TORS appears to yield similar oncologic outcomes and functional outcomes to traditional techniques and non-operative treatment with a possible benefit on long-term quality of life. The future offers exciting opportunities to combine TORS and radiotherapy in unique ways. However, further research is urgently needed to clarify the indications for adjuvant therapy following TORS resections. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/31097824; info:eu-repo/semantics/altIdentifier/wos/WOS:000489652700002; volume:39; issue:2; firstpage:75; lastpage:83; numberofpages:9; journal:ACTA OTORHINOLARYNGOLOGICA ITALICA; http://hdl.handle.net/11573/1374910Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85066847267 |
| DOI: | 10.14639/0392-100X-2199 |
| الإتاحة: | https://doi.org/10.14639/0392-100X-2199Test http://hdl.handle.net/11573/1374910Test |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.6F90F007 |
| قاعدة البيانات: | BASE |
| DOI: | 10.14639/0392-100X-2199 |
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