دورية أكاديمية
Western blot seroindeterminate individuals for human T-lymphotropic virus I/II (HTLV-I/II) in Fortaleza (Brazil): a serological and molecular diagnostic and epidemiological approach
| العنوان: | Western blot seroindeterminate individuals for human T-lymphotropic virus I/II (HTLV-I/II) in Fortaleza (Brazil): a serological and molecular diagnostic and epidemiological approach |
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| المؤلفون: | Santos, Terezinha de Jesus Teixeira, Costa, Carlos MaurÃcio de Castro, Goubau, Patrick, Vandamme, Anne-Mieke, Desmyter, Jan, Van Doren, Sonia, Mota, Rosa M. S., de Castro Costa, Francine Bovy, Oliveira, Ana C. S., Barreto, Vania, Gomes, A. F., Carneiro-Proietti, Anna B., de Bruin, Veralice Meireles Sales, de Sousa, Francisca C. F., Oriá, Reinaldo Barreto |
| المساهمون: | UCL - MD/MIGE - Département de microbiologie, d'immunologie et de génétique, UCL - (SLuc) Service de microbiologie |
| المصدر: | The Brazilian Journal of Infectious Diseases, Vol. 7, no. 3, p. 202-209 (2003) |
| بيانات النشر: | Contexto |
| سنة النشر: | 2003 |
| المجموعة: | DIAL@USL-B (Université Saint-Louis, Bruxelles) |
| مصطلحات موضوعية: | Blotting, Western, Brazil, Cross-Sectional Studies, DNA Primers, Enzyme-Linked Immunosorbent Assay, Female, HTLV-I Infections, HTLV-II Infections, Human T-lymphotropic virus 1, Human T-lymphotropic virus 2, Humans, Male, Polymerase Chain Reaction, Risk Factors, Epidemiology, PCR, HTLV-1/2, Seroindeterminate individuals, Hepatitis, Syphilis, Blood transfusion |
| الوصف: | How to handle Western blot (WB) seroindeterminate individuals for Human T-lymphotropic Virus 1/2 (HTLV-1/2) constitutes a challenge for blood banks and families. We made a cross-sectional study of 191 enzyme linked immunoassay (EIA) reactive individuals from the hematological center (HEMOCE) of Fortaleza (Brazil), examining their serological (WB) and molecular (PCR) diagnosis, and demographic profiles, as well as a possible association of their condition with other infectious pathologies and risk factors. Ethical institutional approval and personal consent were obtained. Out of 191 EIA reactive individuals, 118 were WB seroindeterminate and 73 were seropositive for HTLV-1/2. In the PCR analysis of 41 WB seroindeterminate individuals, 9 (22%) were positive and 32 (78%) were negative for HTLV-1/2. The demographic analysis indicated a trend towards a predominance of males among the seroindeterminate individuals and females in the seropositive ones. The seroindeterminate individuals were younger than the seropositive ones. We did not find any association of these conditions with syphilis, Chagas disease or HIV or hepatitis, and with risk factors such as breast-feeding, blood transfusion, STD (syphilis) and IDU. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1413-8670 1678-4391 |
| العلاقة: | boreal:25789; http://hdl.handle.net/2078.1/25789Test; info:pmid/14499043; urn:ISSN:1413-8670; urn:EISSN:1678-4391 |
| DOI: | 10.1590/S1413-86702003000300005 |
| الإتاحة: | https://doi.org/10.1590/S1413-86702003000300005Test http://hdl.handle.net/2078.1/25789Test |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.6F66E8AE |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 14138670 16784391 |
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| DOI: | 10.1590/S1413-86702003000300005 |