التفاصيل البيبلوغرافية
| العنوان: |
Toward a NOTCH1/FBXW7/RAS/PTEN-based oncogenetic risk classification of adult T-cell acute lymphoblastic leukemia: a Group for Research in Adult Acute Lymphoblastic Leukemia study |
| المؤلفون: |
Trinquand, Amélie, Tanguy-Schmidt, Aline, Ben Abdelali, Raouf, Lambert, Jérôme, Beldjord, Kheira, Lengliné, Etienne, De Gunzburg, Noémie, Payet-Bornet, Dominique, Lhermitte, Ludovic, Mossafa, Hossein, Lhéritier, Véronique, Bond, Jonathan, Huguet, Françoise, Buzyn, Agnès, Leguay, Thibaud, Cahn, Jean-Yves, Thomas, Xavier, Chalandon, Yves, Delannoy, André, Bonmati, Caroline, Maury, Sebastien, Nadel, Bertrand, Macintyre, Elizabeth, Ifrah, Norbert, Dombret, Hervé, Asnafi, Vahid |
| المصدر: |
ISSN: 0732-183X ; Journal of clinical oncology, vol. 31, no. 34 (2013) p. 4333-4342. |
| سنة النشر: |
2013 |
| المجموعة: |
Université de Genève: Archive ouverte UNIGE |
| مصطلحات موضوعية: |
info:eu-repo/classification/ddc/616, Adult, Cell Cycle Proteins/genetics, DNA Mutational Analysis, Disease-Free Survival, F-Box Proteins/genetics, Female, GTP Phosphohydrolases/genetics, Gene Deletion, Genetic Predisposition to Disease, Humans, Kaplan-Meier Estimate, Male, Membrane Proteins/genetics, Multivariate Analysis, Mutation, PTEN Phosphohydrolase/genetics, Phenotype, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/classification/genetics/mortality/therapy, Predictive Value of Tests, Proportional Hazards Models, Proto-Oncogene Proteins/genetics, Receptor, Notch1/genetics, Risk Factors, Time Factors, Ubiquitin-Protein Ligases/genetics, Young Adult, Ras Proteins/genetics |
| الوصف: |
The Group for Research in Adult Acute Lymphoblastic Leukemia (GRAALL) recently reported a significantly better outcome in T-cell acute lymphoblastic leukemia (T-ALL) harboring NOTCH1 and/or FBXW7 (N/F) mutations compared with unmutated T-ALL. Despite this, one third of patients with N/F-mutated T-ALL experienced relapse. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| العلاقة: |
info:eu-repo/semantics/altIdentifier/pmid/24166518; https://archive-ouverte.unige.ch/unige:37149Test; unige:37149 |
| الإتاحة: |
https://doi.org/10.1200/JCO.2012.48.5292Test
https://archive-ouverte.unige.ch/unige:37149Test |
| حقوق: |
info:eu-repo/semantics/openAccess |
| رقم الانضمام: |
edsbas.6EE81FA9 |
| قاعدة البيانات: |
BASE |
