التفاصيل البيبلوغرافية
| العنوان: |
Drug delivery in thermo-responsive silicone catheters by grafting of N-vinylcaprolactam using gamma radiation |
| المؤلفون: |
Ramirez-Fuentes, Manuel U., Duarte-Peña, Lorena, Bucio, Emilio |
| المساهمون: |
Dirección General de Asuntos del Personal Académico, Universidad Nacional Autónoma de México |
| المصدر: |
MRS Communications ; ISSN 2159-6867 |
| بيانات النشر: |
Springer Science and Business Media LLC |
| سنة النشر: |
2024 |
| مصطلحات موضوعية: |
General Materials Science |
| الوصف: |
Radiation-induced graft polymerization of poly(N-vinylcaprolactam) onto silicone catheters by direct irradiation method was studied. The effects of the irradiation dose, as well as the monomer concentration, on the grafting efficiency were studied. The conditions for achieving maximum grafting yield were observed at 30% of monomer concentration in toluene at 50 kGy. The graft polymerization was examined by different characterization methods, including measurements such as thermogravimetric analysis, infrared, water contact angle, and swelling. The temperature-responsive behavior of smart grafted copolymer was studied by swelling at different temperatures. Differently from pristine silicone catheter, the N-vinylcaprolactam-grafted catheters were able to load vancomycin and sustain the release for 30 h. Graphical abstract |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| DOI: |
10.1557/s43579-024-00528-5 |
| DOI: |
10.1557/s43579-024-00528-5.pdf |
| DOI: |
10.1557/s43579-024-00528-5/fulltext.html |
| الإتاحة: |
https://doi.org/10.1557/s43579-024-00528-5Test |
| حقوق: |
https://creativecommons.org/licenses/by/4.0Test ; https://creativecommons.org/licenses/by/4.0Test |
| رقم الانضمام: |
edsbas.6EE47CBE |
| قاعدة البيانات: |
BASE |
