دورية أكاديمية
Systemic immune modulation by stereotactic radiotherapy in early-stage lung cancer
| العنوان: | Systemic immune modulation by stereotactic radiotherapy in early-stage lung cancer |
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| المؤلفون: | Gkika, Eleni, Firat, Elke, Adebahr, Sonja, Graf, Erika, Popp, Ilinca, Radicioni, Gianluca, Lo, Simon S., Nestle, Ursula, Nicolay, Nils H., Niedermann, Gabriele, Duda, Dan G., Grosu, Anca-Ligia |
| المصدر: | npj precision oncology. - 7, 1 (2023) , 24, ISSN: 2397-768X |
| سنة النشر: | 2023 |
| المجموعة: | University of Freiburg: FreiDok |
| الوصف: | We performed a prospective study of circulating immune cell changes after stereotactic body radiotherapy (SBRT) in 50 early-stage NSCLC patients. We found no significant increase in CD8+ cytotoxic T lymphocytes at first follow-up (the primary endpoint) but detected a significant increase in expanding Ki-67+CD8+ and Ki-67+CD4+ T-cell fractions in patients treated with 10 Gy or less per fraction. SBRT can induce significant expansion in circulating effector T-cells immediately post-treatment. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | |
| اللغة: | English |
| العلاقة: | https://freidok.uni-freiburg.de/data/234393Test |
| DOI: | 10.1038/s41698-023-00358-z |
| الإتاحة: | https://doi.org/10.1038/s41698-023-00358-zTest https://freidok.uni-freiburg.de/data/234393Test https://nbn-resolving.org/urn:nbn:de:bsz:25-freidok-2343934Test https://freidok.uni-freiburg.de/dnb/download/234393Test |
| حقوق: | free |
| رقم الانضمام: | edsbas.6D90EFCA |
| قاعدة البيانات: | BASE |
| DOI: | 10.1038/s41698-023-00358-z |
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