دورية أكاديمية
Differential associations between body composition indices and neurodevelopment during early life in term-born infants: findings from the Pakistan cohort: Multi-Center Body Composition Reference Study
| العنوان: | Differential associations between body composition indices and neurodevelopment during early life in term-born infants: findings from the Pakistan cohort: Multi-Center Body Composition Reference Study |
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| المؤلفون: | Ariff, Shabina, Aamir, Almas, Young, Aneurin, Sikanderali, Laila, Rizvi, Arjumand, Shaheen, Fariha, Khan, Gul Nawaz, Soofi, Sajid, Fernandes, Michelle |
| سنة النشر: | 2023 |
| المجموعة: | University of Southampton: e-Prints Soton |
| الوصف: | Objective: we examined associations between fat free mass (FFM) and fat mass (FM) accretion during the first 1000 days of life and neurodevelopment in term-born, low-risk infants from Karachi, Pakistan. Design: prospective, observational study nested within the larger Multi-Center Body Composition Reference Study. FFM, FM, and fat% were estimated using measured deuterium dilution method. Neurodevelopmental outcomes were assessed at 24 months on the INTER-NDA (INTERGROWTH-21st Project Neurodevelopment Assessment) (n = 132). Results: children with gross motor delays had significantly lower FFM at 18 months (8.01 ± 0.97 kg vs. 7.55 ± 0.20 kg). Children with positive and negative behavior problems had significantly higher fat% at 24 months (20.62 ± 4.30% vs. 18.23 ± 5.46%) and 20.89 ± 4.24% vs. 18.54 ± 5.38%). No associations remained significant after adjusting for covariates. Trajectory modeling showed that between 12 and 18 months, negative behavior scores changed by 13.8 points for every standard deviation change in fat accretion. Conclusions: our findings highlight the importance of balancing neurodevelopment and metabolic risk when designing nutritional interventions for young children. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | text |
| اللغة: | English |
| العلاقة: | https://eprints.soton.ac.uk/483410/1/s41430_023_01296_6.pdfTest; Ariff, Shabina, Aamir, Almas, Young, Aneurin, Sikanderali, Laila, Rizvi, Arjumand, Shaheen, Fariha, Khan, Gul Nawaz, Soofi, Sajid and Fernandes, Michelle (2023) Differential associations between body composition indices and neurodevelopment during early life in term-born infants: findings from the Pakistan cohort: Multi-Center Body Composition Reference Study. European Journal of Clinical Nutrition. (doi:10.1038/s41430-023-01296-6 ). |
| الإتاحة: | https://doi.org/10.1038/s41430-023-01296-6Test https://eprints.soton.ac.uk/483410Test/ https://eprints.soton.ac.uk/483410/1/s41430_023_01296_6.pdfTest |
| حقوق: | cc_by_4 |
| رقم الانضمام: | edsbas.6C79AAEE |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |