التفاصيل البيبلوغرافية
| العنوان: |
Geriatric Nutritional Risk Index Combined with Calf Circumference Can be a Good Predictor of Prognosis in Patients Undergoing Surgery for Gastric or Colorectal Cancer |
| المؤلفون: |
Zheng, Xin, Shi, Jin-Yu, Wang, Zi-Wen, Ruan, Guo-Tian, Ge, Yi-Zhong, Lin, Shi-Qi, Liu, Chen-An, Chen, Yue, Xie, Hai-Lun, Song, Meng-Meng, Liu, Tong, Yang, Ming, Liu, Xiao-Yue, Deng, Li, Cong, Ming-Hua, Shi, Han-Ping |
| المساهمون: |
China Postdoctoral Science Foundation, Beijing Postdoctoral Research Foundation, National Natural Science Foundation of China, China National Postdoctoral Program for Innovative Talents, The National Key Research and Development Program |
| المصدر: |
Cancer Control ; volume 31 ; ISSN 1073-2748 1526-2359 |
| بيانات النشر: |
SAGE Publications |
| سنة النشر: |
2024 |
| مصطلحات موضوعية: |
Oncology, Hematology, General Medicine |
| الوصف: |
Objectives To explore the effect of combined hematological and physical measurement indicators on the prognosis of patients undergoing surgery for gastric or colorectal cancer and to screen for the best prognostic indicators. Introduction Gastric and colorectal cancer is a widespread health concern worldwide and one of the major contributors to cancer-related death. The hematological and physical measurement indicators have been shown to associate with the prognosis of patients undergoing surgery for gastric or colorectal cancer, respectively, but it is still unclear whether the combination of the two can reflect the prognosis more effectively. Methods Thirteen hematological indicators and 5 physical measurement indicators were selected in this study, and the most promising ones were screened using LASSO regression. Then, the best prognostic indicators were selected by time-ROC curves. Survival curves were constructed using the Kaplan–Meier method, and the effects of hematological and physical measurement indicators on the prognosis of patients undergoing surgery for gastric or colorectal cancers were evaluated by Cox proportional risk regression analysis. In addition, the relationship between hematological and physical measurement indicators on secondary outcomes, including length of stay, hospitalization costs, intensive care unit (ICU) admission, and patients’ subjective global assessment scores (PGSGA), was explored. Results After initial screening, among the hematological indicators, the geriatric nutritional risk index (GNRI) showed the highest mean area under the curve (AUC) values. Among body measures, calf circumference (CC) showed the highest mean AUC value. Further analyses showed that the combination of combined nutritional prognostic index (GNRI) and calf circumference (CC) (GNRI-CC) had the best performance in predicting the prognosis of patients undergoing surgery for gastric or colorectal cancers. Low GNRI, low CC, and low GNRI-low CC increased the risk of death by 44%, 48%, and 104%, ... |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| DOI: |
10.1177/10732748241230888 |
| الإتاحة: |
https://doi.org/10.1177/10732748241230888Test |
| حقوق: |
https://creativecommons.org/licenses/by-nc/4.0Test/ |
| رقم الانضمام: |
edsbas.68CC54D8 |
| قاعدة البيانات: |
BASE |
