دورية أكاديمية
Intralesional 5-Fluorouracil for Keloids: A Systematic Review ...
العنوان: | Intralesional 5-Fluorouracil for Keloids: A Systematic Review ... |
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المؤلفون: | King, Aliyah, Guirguis, Marina, Satkunanathan, Seyyon, Saad, Mysa, Bose, Reetesh |
بيانات النشر: | SAGE Journals |
سنة النشر: | 2024 |
المجموعة: | DataCite Metadata Store (German National Library of Science and Technology) |
مصطلحات موضوعية: | Medicine |
الوصف: | Keloids are benign, fibroproliferative dermal tumours, often arising after trauma, that are more common in darker skin types. Numerous therapeutic options have been employed for the treatment of keloids; however, there is no one gold standard approach. Five-fluorouracil, a potent chemotherapeutic agent, has emerged as a promising therapeutic option. Therefore, this systematic review, using Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, focused on providing a broad overview of the use of 5-fluorouracil for the management of keloids. Forty studies (2325 patients) met inclusion criteria and investigated 5-fluorouracil for keloid management, with 19 studies (1043 patients) including a 5-fluorouracil monotherapy group. Five-fluorouracil monotherapy demonstrated consistent keloid improvement with >254 keloids injected across various anatomical regions. Five-fluorouracil monotherapy was most often compared to intralesional triamcinolone acetonide, utilizing the Patient ... |
نوع الوثيقة: | article in journal/newspaper |
اللغة: | unknown |
DOI: | 10.25384/sage.c.7259044 |
الإتاحة: | https://doi.org/10.25384/sage.c.7259044Test https://sage.figshare.com/collections/Intralesional_5-Fluorouracil_for_Keloids_A_Systematic_Review/7259044Test |
حقوق: | Creative Commons Attribution 4.0 International ; https://creativecommons.org/licenses/by/4.0/legalcodeTest ; cc-by-4.0 |
رقم الانضمام: | edsbas.67D0206E |
قاعدة البيانات: | BASE |
DOI: | 10.25384/sage.c.7259044 |
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