دورية أكاديمية
New Horizons: Novel Adrenal Regenerative Therapies
| العنوان: | New Horizons: Novel Adrenal Regenerative Therapies |
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| المؤلفون: | Bornstein, Stefan R, Malyukov, Maria, Heller, Carolin, Ziegler, Christian G, Ruiz-Babot, Gerard, Schedl, Andreas, Ludwig, Barbara, Steenblock, Charlotte |
| المصدر: | Bornstein, Stefan R; Malyukov, Maria; Heller, Carolin; Ziegler, Christian G; Ruiz-Babot, Gerard; Schedl, Andreas; Ludwig, Barbara; Steenblock, Charlotte (2020). New Horizons: Novel Adrenal Regenerative Therapies. Journal of Clinical Endocrinology & Metabolism, 105(9):3103-3107. |
| بيانات النشر: | Oxford University Press |
| سنة النشر: | 2020 |
| المجموعة: | University of Zurich (UZH): ZORA (Zurich Open Repository and Archive |
| مصطلحات موضوعية: | Clinic for Endocrinology and Diabetology, 610 Medicine & health |
| الوصف: | Adrenal insufficiency requires lifelong corticoid replacement therapies. However, current therapies are not able to replace the physiological circadian pattern of the adrenal cortex and are associated with many metabolic, vascular, neuroendocrine and mental perturbations. Therefore, regenerative and more curative strategies would be desirable. In the current perspective, we describe emerging new regenerative therapies for the treatment of adrenal insufficiency. Especially, we discuss gene therapy and cell replacement strategies. Furthermore, we discuss how adrenal cells might be used as a source for regenerative therapies of non-adrenal neurodegenerative diseases such as Parkinson's disease. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 0021-972X |
| العلاقة: | https://www.zora.uzh.ch/id/eprint/188511/1/dgaa438.pdfTest; info:pmid/32629476; urn:issn:0021-972X |
| DOI: | 10.5167/uzh-188511 |
| DOI: | 10.1210/clinem/dgaa438 |
| الإتاحة: | https://doi.org/10.5167/uzh-18851110.1210/clinem/dgaa438Test https://www.zora.uzh.ch/id/eprint/188511Test/ https://www.zora.uzh.ch/id/eprint/188511/1/dgaa438.pdfTest |
| حقوق: | info:eu-repo/semantics/openAccess ; Creative Commons: Attribution 4.0 International (CC BY 4.0) ; http://creativecommons.org/licenses/by/4.0Test/ |
| رقم الانضمام: | edsbas.67CA1406 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 0021972X |
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| DOI: | 10.5167/uzh-188511 |