دورية أكاديمية
Convection Enhanced Delivery of Topotecan for Gliomas: A Single-Center Experience
| العنوان: | Convection Enhanced Delivery of Topotecan for Gliomas: A Single-Center Experience |
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| المؤلفون: | Pavan S. Upadhyayula, Eleonora F. Spinazzi, Michael G. Argenziano, Peter Canoll, Jeffrey N. Bruce |
| المصدر: | Pharmaceutics; Volume 13; Issue 1; Pages: 39 |
| بيانات النشر: | Multidisciplinary Digital Publishing Institute |
| سنة النشر: | 2020 |
| المجموعة: | MDPI Open Access Publishing |
| مصطلحات موضوعية: | convection enhanced delivery, glioma, glioblastoma, topotecan |
| الوصف: | A key limitation to glioma treatment involves the blood brain barrier (BBB). Convection enhanced delivery (CED) is a technique that uses a catheter placed directly into the brain parenchyma to infuse treatments using a pressure gradient. In this manuscript, we describe the physical principles behind CED along with the common pitfalls and methods for optimizing convection. Finally, we highlight our institutional experience using topotecan CED for the treatment of malignant glioma. |
| نوع الوثيقة: | text |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | Drug Delivery and Controlled Release; https://dx.doi.org/10.3390/pharmaceutics13010039Test |
| DOI: | 10.3390/pharmaceutics13010039 |
| الإتاحة: | https://doi.org/10.3390/pharmaceutics13010039Test |
| حقوق: | https://creativecommons.org/licenses/by/4.0Test/ |
| رقم الانضمام: | edsbas.66D74F1C |
| قاعدة البيانات: | BASE |
| DOI: | 10.3390/pharmaceutics13010039 |
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