دورية أكاديمية

Dynamics of antibodies to Ebolaviruses in an Eidolon helvum bat colony in Cameroon

التفاصيل البيبلوغرافية
العنوان: Dynamics of antibodies to Ebolaviruses in an Eidolon helvum bat colony in Cameroon
المؤلفون: Meta Djomsi, Dowbiss, Mba Djonzo, Flaubert Auguste, Ndong Bass, Innocent, Champagne, Maëliss, Lacroix, Audrey, Thaurignac, Guillaume, Esteban, Amandine, De Nys, Hélène, Bourgarel, Mathieu, Akoachere, Jane-Francis, Delaporte, Eric, Ayouba, Ahidjo, Cappelle, Julien, Mpoudi Ngole, Eitel, Peeters, Martine
المصدر: Viruses
سنة النشر: 2022
المجموعة: CIRAD: Agritrop (Centre de coopération internationale en recherche agronomique pour le développement)
مصطلحات موضوعية: L73 - Maladies des animaux, S50 - Santé humaine, Ebolavirus, Chiroptera, anticorps, collecte de données, analyse de données, sérologie, immunodiagnostic, relation hôte pathogène, http://aims.fao.org/aos/agrovoc/c_4d8a8e7bTest, http://aims.fao.org/aos/agrovoc/c_1560Test, http://aims.fao.org/aos/agrovoc/c_493Test, http://aims.fao.org/aos/agrovoc/c_2128Test, http://aims.fao.org/aos/agrovoc/c_15962Test, http://aims.fao.org/aos/agrovoc/c_27081Test, http://aims.fao.org/aos/agrovoc/c_27555Test, http://aims.fao.org/aos/agrovoc/c_34017Test, http://aims.fao.org/aos/agrovoc/c_1229Test
جغرافية الموضوع: Cameroun
الوصف: The ecology of ebolaviruses is still poorly understood and the role of bats in outbreaks needs to be further clarified. Straw-colored fruit bats (Eidolon helvum) are the most common fruit bats in Africa and antibodies to ebolaviruses have been documented in this species. Between December 2018 and November 2019, samples were collected at approximately monthly intervals in roosting and feeding sites from 820 bats from an Eidolon helvum colony. Dried blood spots (DBS) were tested for antibodies to Zaire, Sudan, and Bundibugyo ebolaviruses. The proportion of samples reactive with GP antigens increased significantly with age from 0–9/220 (0–4.1%) in juveniles to 26–158/225 (11.6–70.2%) in immature adults and 10–225/372 (2.7–60.5%) in adult bats. Antibody responses were lower in lactating females. Viral RNA was not detected in 456 swab samples collected from 152 juvenile and 214 immature adult bats. Overall, our study shows that antibody levels increase in young bats suggesting that seroconversion to Ebola or related viruses occurs in older juvenile and immature adult bats. Multiple year monitoring would be needed to confirm this trend. Knowledge of the periods of the year with the highest risk of Ebolavirus circulation can guide the implementation of strategies to mitigate spill-over events.
نوع الوثيقة: article in journal/newspaper
وصف الملف: text
اللغة: English
العلاقة: http://agritrop.cirad.fr/600701Test/; Dynamics of antibodies to Ebolaviruses in an Eidolon helvum bat colony in Cameroon. Meta Djomsi Dowbiss, Mba Djonzo Flaubert Auguste, Ndong Bass Innocent, Champagne Maëliss, Lacroix Audrey, Thaurignac Guillaume, Esteban Amandine, De Nys Hélène, Bourgarel Mathieu, Akoachere Jane-Francis, Delaporte Eric, Ayouba Ahidjo, Cappelle Julien, Mpoudi Ngole Eitel, Peeters Martine. 2022. Viruses, 14 (3):560, 13 p.https://doi.org/10.3390/v14030560Test; http://agritrop.cirad.fr/600701/1/viruses-14-00560.pdfTest
DOI: 10.3390/v14030560
الإتاحة: https://doi.org/10.3390/v14030560Test
http://agritrop.cirad.fr/600701Test/
http://agritrop.cirad.fr/600701/1/viruses-14-00560.pdfTest
حقوق: cc_by ; info:eu-repo/semantics/openAccess ; https://creativecommons.org/licenses/by/4.0Test/
رقم الانضمام: edsbas.6561B57
قاعدة البيانات: BASE