دورية أكاديمية
Occupational exposure to antineoplastic drugs: Taking activity into account to rethink preventive actions ; Exposition professionnelle aux médicaments anticancéreux : vers la prise en compte de l’activité pour repenser les actions de prévention
| العنوان: | Occupational exposure to antineoplastic drugs: Taking activity into account to rethink preventive actions ; Exposition professionnelle aux médicaments anticancéreux : vers la prise en compte de l’activité pour repenser les actions de prévention |
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| المؤلفون: | Lamarque, V., Swierczynski, Guillaume, Verdun- Esquer, Catherine, Léger, C., Canal-Raffin, Mireille, Garrigou, A., Nascimento, Adelaide |
| المساهمون: | Centre de recherche sur le travail et le développement (CRTD), Conservatoire National des Arts et Métiers CNAM (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM), Cancer environnement (EPICENE ), Bordeaux population health (BPH), Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM), CHU Bordeaux, HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM), Sciences pour l'Action et le Développement : Activités, Produits, Territoires (SADAPT), AgroParisTech-Université Paris-Saclay-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), ANR-19-CE26-0021,ITAPAR,Innovation and Transformation for Prevention Activity of Professional Risks(2019) |
| المصدر: | ISSN: 1775-8785 ; Archives des Maladies Professionnelles et de L'Environnement ; https://hal.science/hal-04394101Test ; Archives des Maladies Professionnelles et de L'Environnement, 2024, 85 (1), pp.101945. ⟨10.1016/j.admp.2023.101945⟩ ; https://www.sciencedirect.com/science/article/pii/S1775878523002394Test. |
| بيانات النشر: | HAL CCSD Elsevier Masson |
| سنة النشر: | 2024 |
| مصطلحات موضوعية: | Antineoplastic drugs, Ergonomics, Prevention, Occupational exposures, Carcinogens mutagens reprotoxic, Médicaments anticancéreux, Ergonomie, Prévention, Expositions professionnelles, Cancérogènes mutagènes reprotoxique, [SHS]Humanities and Social Sciences |
| الوصف: | International audience ; Despite preventive efforts to reduce occupational exposure to antineoplastic drugs (ADs), the problem remains. The literature on the subject points to the need to characterize, assess and train professionals. In this article, using ergotoxicology as a tool, we will look at how multiple exposures to multiple nuisances and the associated protective measures arise in the work of healthcare workers, by means of hand-wiping samples and self-confrontation interviews. Hand wiping carried out before and after actions identified as potentially exposing, revealed the presence of ADs in all samples (n = 20). The compound handled on the sampling day was found in only 25% of the samples. Only two samples (out of 9) showed an increase in the level of hand contamination after a potentially exposing action. Although these data have helped to reveal part of the enigma of exposure to ADs, they do not yet allow us to characterize it. Nonetheless, our methods have enabled us to identify the determinants of contamination at different activity levels, which still need to be examined in greater depth in the rest of the prevention project. The interview data show that, despite a lack of training, carers can identify potential sources and areas of exposure. Our results lead us to believe that our methods have enabled carers to enter a “zone of proximal development”, where their knowledge of biological risks could serve as a resource for better chemical risk management. These data also show that carers take action on a daily basis in the face of multiple exposures, and produce protective measures that go beyond the prescribed protective equipment. Given the routes of exposure and modes of transmission of biological risk contamination, the protective actions developed for this risk could contribute to the development of a new form of intervention for ADs. ; Malgré les efforts réalisés en prévention pour réduire l’exposition professionnelle aux médicaments anticancéreux (MAC), ce problème reste d’actualité. La ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | French |
| العلاقة: | hal-04394101; https://hal.science/hal-04394101Test |
| DOI: | 10.1016/j.admp.2023.101945 |
| الإتاحة: | https://doi.org/10.1016/j.admp.2023.101945Test https://hal.science/hal-04394101Test |
| حقوق: | http://creativecommons.org/licenses/by-nc-ndTest/ |
| رقم الانضمام: | edsbas.643D08E2 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.admp.2023.101945 |
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