دورية أكاديمية

Vascular territorial segmentation and volumetric blood flow measurement using dynamic contrast enhanced magnetic resonance angiography of the brain

التفاصيل البيبلوغرافية
العنوان: Vascular territorial segmentation and volumetric blood flow measurement using dynamic contrast enhanced magnetic resonance angiography of the brain
المؤلفون: Geri, Oren, Shiran, Shelly I, Roth, Jonathan, Artzi, Moran, Ben-Sira, Liat, Ben Bashat, Dafna
المصدر: Journal of Cerebral Blood Flow & Metabolism ; volume 37, issue 10, page 3446-3456 ; ISSN 0271-678X 1559-7016
بيانات النشر: SAGE Publications
سنة النشر: 2017
الوصف: This study proposes a method for territorial segmentation and volumetric flow rate (VFR) distribution measurement of cerebral territories based on time-resolved contrast enhanced magnetic-resonance-angiography (MRA). The method uses an iterative region-growing algorithm based on bolus-arrival-time with increased temporal resolution. Eight territories were segmented: (1) right and (2) left internal carotid arteries, including the middle cerebral artery (ICA+MCA), excluding the anterior cerebral arteries (ACA); (3) right and left ACA (R+L-ACA); (4) right and (5) left external carotid arteries (ECA); (6) right and (7) left posterior cerebral arteries (PCA); and (8) vertebrobasilar territory. VFR percentage, relative to the entire brain (rVFR), was measured based on territorial volume as a function of time. Mean rVFR values of fifteen healthy subjects were: ICA+MCA = 23 ± 2%, R + L-ACA = 17 ± 3%, ECA = 4 ± 2%, PCA = 12 ± 2%, and vertebrobasilar territory = 31 ± 4%. Excluding the ECA-rVFR, which is underestimated, these values are comparable to previously reported values. Six subjects were scanned twice, demonstrating comparable and even higher reproducibility than previously reported using phase-contrast, yet with faster scan time (∼1 min). This method was implemented in one patient with MCA occlusion and one with Moyamoya syndrome scanned before and after bypass surgery, demonstrating its clinical potential for quantitative assessment of the degree of occlusion and the effect of surgery.
نوع الوثيقة: article in journal/newspaper
اللغة: English
DOI: 10.1177/0271678x17702394
DOI: 10.1177/0271678X17702394
الإتاحة: https://doi.org/10.1177/0271678x17702394Test
حقوق: http://journals.sagepub.com/page/policies/text-and-data-mining-licenseTest
رقم الانضمام: edsbas.63E1424
قاعدة البيانات: BASE