دورية أكاديمية
Representative Sequencing:Unbiased Sampling of Solid Tumor Tissue
| العنوان: | Representative Sequencing:Unbiased Sampling of Solid Tumor Tissue |
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| المؤلفون: | Litchfield, Kevin, Stanislaw, Stacey, Spain, Lavinia, Gallegos, Lisa L., Rowan, Andrew, Schnidrig, Desiree, Rosenbaum, Heidi, Harle, Alexandre, Au, Lewis, Hill, Samantha M., Tippu, Zayd, Thomas, Jennifer, Thompson, Lisa, Xu, Hang, Horswell, Stuart, Barhoumi, Aoune, Jones, Carol, Leith, Katherine F., Burgess, Daniel L., Watkins, Thomas B.K., Lim, Emilia, Birkbak, Nicolai J., Lamy, Philippe, Nordentoft, Iver, Dyrskjøt, Lars, Pickering, Lisa, Hazell, Stephen, Jamal-Hanjani, Mariam, Larkin, James, Swanton, Charles, Alexander, Nelson, Turajlic, Samra |
| المصدر: | Litchfield , K , Stanislaw , S , Spain , L , Gallegos , L L , Rowan , A , Schnidrig , D , Rosenbaum , H , Harle , A , Au , L , Hill , S M , Tippu , Z , Thomas , J , Thompson , L , Xu , H , Horswell , S , Barhoumi , A , Jones , C , Leith , K F , Burgess , D L , Watkins , T B K , Lim , E , Birkbak , N J , Lamy , P , .... |
| سنة النشر: | 2020 |
| المجموعة: | Aarhus University: Research |
| مصطلحات موضوعية: | biomarkers, homogenization, molecular profiling, representative sampling, tumor hetereogeneity, tumor mutational burden, tumor sampling, tumor sequencing |
| الوصف: | Solid tumors are under-sampled in the clinic, such that only 0.0005% of initial tumor volume is used as input for diagnostic testing. Litchfield et al. apply the principles of representative sampling to implement an unbiased tumor sampling approach that improves the reproducibility and accuracy of next-generation sequencing. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1016/j.celrep.2020.107550 |
| الإتاحة: | https://doi.org/10.1016/j.celrep.2020.107550Test https://pure.au.dk/portal/da/publications/representative-sequencingTest(ec691e14-56b9-423f-9890-27446514de71).html http://www.scopus.com/inward/record.url?scp=85084147969&partnerID=8YFLogxKTest |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.63450D51 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.celrep.2020.107550 |
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