التفاصيل البيبلوغرافية
| العنوان: |
Detection of dengue virus serotype 1 in central nervous system of a child in Bandung, West Java: A case report |
| المؤلفون: |
Alisjahbana, Dewi Hawani, Nurmawati, Syndi, Hakim, Dzulfikar DL, Milanti, Mia, Dewi, Yora Permata, Johar, Edison, Myint, Khin Saw Aye, Lederman, Jeremy P, Powers, Ann M, Alisjahbana, Bachti, Antonjaya, Ungke |
| المصدر: |
SAGE Open Medical Case Reports ; volume 9, page 2050313X2110343 ; ISSN 2050-313X 2050-313X |
| بيانات النشر: |
SAGE Publications |
| سنة النشر: |
2021 |
| مصطلحات موضوعية: |
General Medicine |
| الوصف: |
Central nervous system involvement of dengue virus is increasingly reported from endemic areas. This study describes the clinical characteristics and laboratory features of a pediatric patient enrolled in a central nervous system illness study conducted in 2017–2018 to identify viral and bacterial etiologies in Indonesian children. Dengue diagnostics including molecular and serological testing were performed on an encephalitis patient who presented with both classical dengue and neurological clinical symptoms. Dengue virus serotype 1 RNA was detected in both cerebrospinal fluid and serum by serotype-specific reverse transcription polymerase chain reaction, and the E gene was successfully sequenced. Anti-dengue virus immunoglobulin M was detected in both admission and discharge sera, whereas anti-dengue virus immunoglobulin G was identified only in the discharge serum. This study describes the central nervous system complications in a case with dengue virus infection in West Java, Indonesia, and highlights the potential for dengue virus serotype 1, a serotype rarely associated with neurotropism, to cause encephalitis. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| DOI: |
10.1177/2050313x211034393 |
| DOI: |
10.1177/2050313X211034393 |
| الإتاحة: |
https://doi.org/10.1177/2050313x211034393Test |
| حقوق: |
https://creativecommons.org/licenses/by-nc/4.0Test/ |
| رقم الانضمام: |
edsbas.624DCA40 |
| قاعدة البيانات: |
BASE |
