التفاصيل البيبلوغرافية
| العنوان: |
Association between Gestational Weight Gain and Risk of Hypertensive Disorders of Pregnancy among Women with Obesity: A Multicenter Retrospective Cohort Study in Japan |
| المؤلفون: |
Momoka Ito, Hyo Kyozuka, Tomoko Yamaguchi, Misa Sugeno, Tsuyoshi Murata, Tsuyoshi Hiraiwa, Fumihiro Ito, Daisuke Suzuki, Toma Fukuda, Shun Yasuda, Keiya Fujimori, Yasuhisa Nomura |
| المصدر: |
Nutrients; Volume 15; Issue 11; Pages: 2428 |
| بيانات النشر: |
Multidisciplinary Digital Publishing Institute |
| سنة النشر: |
2023 |
| المجموعة: |
MDPI Open Access Publishing |
| مصطلحات موضوعية: |
body mass index, gestational weight gain, obesity, preconception care, hypertensive disorders of pregnancy |
| جغرافية الموضوع: |
agris |
| الوصف: |
The relationship between weight gain during pregnancy and the onset of hypertensive disorders of pregnancy in women with pre-pregnancy obesity remains unclear. We examined the effects of weight gain during pregnancy on hypertensive disorders of pregnancy among women with pre-pregnancy body mass index (BMI) ≥ 25.0 kg/m2. This multicenter retrospective cohort study included nullipara women who delivered at two units in Japan between 1 January 2013, and 31 December 2020. Singleton primipara (n = 3040) were categorized into two pre-pregnancy BMI groups: 25.0–<30.0, and ≥30.0 kg/m2. Using multiple logistic regression analyses (reported as adjusted odds ratio and 95% confidence interval), gestational weight gain effects on overall hypertensive disorders of pregnancy, gestational hypertension, and pre-eclampsia were determined. Gestational weight gain increased hypertensive disorders of pregnancy (1.09, 1.03–1.16, p < 0.05) and pre-eclampsia risk (1.10, 1.01–1.20, p < 0.05) among the BMI 25.0–<30.0 kg/m2 group and hypertensive disorders of pregnancy risk among the ≥30.0 kg/m2 group (1.07, 1.00–1.05, p < 0.05). Using receiver operating characteristic curve analyses, among the BMI 25.0–<30.0 kg/m2 group, for hypertensive disorders of pregnancy (area under the curve [AUC], 0.63, p < 0.05) and pre-eclampsia (AUC, 0.62; p < 0.05), the weight gain cut-off was 10.5 and 10.6 kg, with sensitivity/specificity of 0.47/0.73 and 0.50/0.73, respectively. For the BMI ≥30.0 kg/m2 group (AUC, 0.63, p < 0.05), the cut-off was 3.5 kg (sensitivity/specificity, 0.75/0.49). The optimal gestational weight gain for reducing hypertensive disorders of pregnancy among women with a pre-pregnancy BMI > 25 kg/m2 may facilitate personalized pre-conception counseling among women with obesity. |
| نوع الوثيقة: |
text |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| العلاقة: |
Nutrition in Women; https://dx.doi.org/10.3390/nu15112428Test |
| DOI: |
10.3390/nu15112428 |
| الإتاحة: |
https://doi.org/10.3390/nu15112428Test |
| حقوق: |
https://creativecommons.org/licenses/by/4.0Test/ |
| رقم الانضمام: |
edsbas.614B349D |
| قاعدة البيانات: |
BASE |
