دورية أكاديمية

C-reactive protein levels in non-obese pregnant women with gestational diabetes

التفاصيل البيبلوغرافية
العنوان: C-reactive protein levels in non-obese pregnant women with gestational diabetes
المؤلفون: Rota, Simin, Yıldırım, BaÅŸak, Duman, K., Kaptanoglu, B., Aybek, Hülya, Kaleli, Babür
سنة النشر: 2005
المجموعة: Pamukkale University Repository / Pamukkale Üniversitesi Açık Erişim Arşivi
مصطلحات موضوعية: CRP, Female, BMI, Gestational diabetes, Pregnancy, Subclinical inflammation, C reactive protein, glucose, adult, age, article, body mass, clinical article, controlled study, diet restriction, gestational age, glucose blood level, glucose intolerance, human, inflammation, metabolic parameters, oral glucose tolerance test, parity, pathophysiology, pregnancy diabetes mellitus, protein blood level, second trimester pregnancy, statistical analysis, third trimester pregnancy, variance
الوصف: A low-grade systemic inflammation is concomitant in diabetes. There is a pathophysiological relation between gestational diabetes mellitus and type 2 diabetes mellitus, which was further supported by significantly elevated risk of type 2 diabetes in women with a history of previous gestational diabetes mellitus. We investigated the relation between low-grade systemic inflammation expressed as C-reactive protein and gestational diabetes in non-obese pregnant women. This study included 20 non-obese pregnant women with gestational diabetes mellitus and 30 non-obese pregnant women without gestational diabetes mellitus as a control group. The body mass index of all the subjects were ;lt; 25 kg/m2. During 26-28 gestational weeks 100-g oral glucose tolerance test was performed and simultaneously fasting C-reactive protein levels were measured. Serum median C-reactive protein level was higher in patients with gestational diabetes mellitus (p = 0.0001). C-reactive protein was strongly associated with glycemic parameters and weight gain during pregnancy. A model consisting of glucose intolerance, age, parity, and weight gain during pregnancy accounted for 61% of the variance in log C-reactive protein. We demonstrated that serum C-reactive protein level was related with gestational diabetes mellitus and weight gain during pregnancy in late second and early third trimesters. © 2005 Tohoku University Medical Press.
نوع الوثيقة: article in journal/newspaper
اللغة: English
تدمد: 0040-8727
العلاقة: Tohoku Journal of Experimental Medicine; Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı; https://hdl.handle.net/11499/4820Test; https://doi.org/10.1620/tjem.206.341Test; 206; 341; 345; 2-s2.0-23944512171; WOS:000230231900009
DOI: 10.1620/tjem.206.341
الإتاحة: https://doi.org/10.1620/tjem.206.341Test
https://hdl.handle.net/11499/4820Test
حقوق: open
رقم الانضمام: edsbas.60CE1CDB
قاعدة البيانات: BASE
الوصف
تدمد:00408727
DOI:10.1620/tjem.206.341