دورية أكاديمية

2018 American College of Rheumatology/National Psoriasis Foundation Guideline for the Treatment of Psoriatic Arthritis

التفاصيل البيبلوغرافية
العنوان: 2018 American College of Rheumatology/National Psoriasis Foundation Guideline for the Treatment of Psoriatic Arthritis
المؤلفون: Singh, Jasvinder A., Guyatt, Gordon, Ogdie, Alexis, Gladman, Dafna D., Deal, Chad, Deodhar, Atul, Dubreuil, Maureen, Dunham, Jonathan, Husni, M. Elaine, Kenny, Sarah, Kwan‐Morley, Jennifer, Lin, Janice, Marchetta, Paula, Mease, Philip J., Merola, Joseph F., Miner, Julie, Ritchlin, Christopher T., Siaton, Bernadette, Smith, Benjamin J., Van Voorhees, Abby S., Jonsson, Anna Helena, Shah, Amit Aakash, Sullivan, Nancy, Turgunbaev, Marat, Coates, Laura C., Gottlieb, Alice, Magrey, Marina, Nowell, W. Benjamin, Orbai, Ana‐Maria, Reddy, Soumya M., Scher, Jose U., Siegel, Evan, Siegel, Michael, Walsh, Jessica A., Turner, Amy S., Reston, James
المساهمون: National Psoriasis Foundation
المصدر: Arthritis Care & Research ; volume 71, issue 1, page 2-29 ; ISSN 2151-464X 2151-4658
بيانات النشر: Wiley
سنة النشر: 2018
المجموعة: Wiley Online Library (Open Access Articles via Crossref)
الوصف: Objective To develop an evidence‐based guideline for the pharmacologic and nonpharmacologic treatment of psoriatic arthritis (PsA), as a collaboration between the American College of Rheumatology (ACR) and the National Psoriasis Foundation (NPF). Methods We identified critical outcomes in PsA and clinically relevant PICO (population/intervention/comparator/outcomes) questions. A Literature Review Team performed a systematic literature review to summarize evidence supporting the benefits and harms of available pharmacologic and nonpharmacologic therapies for PsA. GRADE (Grading of Recommendations Assessment, Development and Evaluation) methodology was used to rate the quality of the evidence. A voting panel, including rheumatologists, dermatologists, other health professionals, and patients, achieved consensus on the direction and the strength of the recommendations. Results The guideline covers the management of active PsA in patients who are treatment‐naive and those who continue to have active PsA despite treatment, and addresses the use of oral small molecules, tumor necrosis factor inhibitors, interleukin‐12/23 inhibitors (IL‐12/23i), IL‐17 inhibitors, CTLA4‐Ig (abatacept), and a JAK inhibitor (tofacitinib). We also developed recommendations for psoriatic spondylitis, predominant enthesitis, and treatment in the presence of concomitant inflammatory bowel disease, diabetes, or serious infections. We formulated recommendations for a treat‐to‐target strategy, vaccinations, and nonpharmacologic therapies. Six percent of the recommendations were strong and 94% conditional, indicating the importance of active discussion between the health care provider and the patient to choose the optimal treatment. Conclusion The 2018 ACR/NPF PsA guideline serves as a tool for health care providers and patients in the selection of appropriate therapy in common clinical scenarios. Best treatment decisions consider each individual patient situation. The guideline is not meant to be proscriptive and should not be used to limit ...
نوع الوثيقة: article in journal/newspaper
اللغة: English
DOI: 10.1002/acr.23789
الإتاحة: https://doi.org/10.1002/acr.23789Test
حقوق: http://onlinelibrary.wiley.com/termsAndConditions#vorTest
رقم الانضمام: edsbas.60AB4131
قاعدة البيانات: BASE