دورية أكاديمية
Effectiveness of radiotherapy to prevent recurrence of heterotopic ossification in patients with spinal cord injury and traumatic head injury: A retrospective case-controlled study
العنوان: | Effectiveness of radiotherapy to prevent recurrence of heterotopic ossification in patients with spinal cord injury and traumatic head injury: A retrospective case-controlled study |
---|---|
المؤلفون: | Thibaud Honore, Marjorie Salga, Amandine Grelier, Philippe Denormandie, Guillaume Genet, Alain Labib, Isabelle Bonan, Francois Genet |
المصدر: | Journal of Rehabilitation Medicine, Vol 52, Iss 5, p jrm00066 (2020) |
بيانات النشر: | Medical Journals Sweden |
سنة النشر: | 2020 |
المجموعة: | Directory of Open Access Journals: DOAJ Articles |
مصطلحات موضوعية: | heterotopic ossification, radiotherapy, recurrence, spinal cord injury, traumatic brain injury, excision, Therapeutics. Pharmacology, RM1-950 |
الوصف: | Objective: To evaluate recurrence and early post-operative complications (sepsis) following surgical excision combined with radiotherapy for trouble-some hip heterotopic ossification in patients with spinal cord injury and traumatic brain injury. Design: Retrospective case-control study. Setting: Data relating to patients with spinal cord injury or traumatic brain injury who underwent surgical excision of hip heterotopic ossification were retrieved from the BANKHO database. Case patients underwent excision + radiotherapy, and controls underwent excision only. Control patients were matched to case patients according to sex and age (± 4 years). Participants: Data from 19 case patients and 76 controls were analysed. Main outcome measure: The primary end-point was recurrence of heterotopic ossification. Secondary end-points were postoperative complications and, more specifically, sepsis that required surgical revision. Results: There was no difference between the odds ratios (OR) for recurrence for each group (OR case group = 0.63, OR spinal cord injury subgroup = 0.45 and OR head injury subgroup = 1.04). The rate of sepsis requiring surgical revision was significantly higher in the case group (p < 0.05). Conclusion: Based on the results of this case-control study, we suggest that radiotherapy should not be combined with surgery in patients with troublesome hip heterotopic ossification undergoing excision. Radiotherapy does not appear to prevent recurrence and, moreover, it is associated with an increased risk of postoperative sepsis. |
نوع الوثيقة: | article in journal/newspaper |
اللغة: | English |
تدمد: | 1650-1977 1651-2081 |
العلاقة: | https://www.medicaljournals.se/jrm/content/html/10.2340/16501977-2692Test; https://doaj.org/toc/1650-1977Test; https://doaj.org/toc/1651-2081Test; https://doaj.org/article/f840816c88f949f89ad30c2dc25781c3Test |
DOI: | 10.2340/16501977-2692 |
الإتاحة: | https://doi.org/10.2340/16501977-2692Test https://doaj.org/article/f840816c88f949f89ad30c2dc25781c3Test |
رقم الانضمام: | edsbas.5FBD269D |
قاعدة البيانات: | BASE |
تدمد: | 16501977 16512081 |
---|---|
DOI: | 10.2340/16501977-2692 |