دورية أكاديمية
Hepatic follicular lymphoma in an old patient with Crohn’s disease: a rare case and review of the literature
| العنوان: | Hepatic follicular lymphoma in an old patient with Crohn’s disease: a rare case and review of the literature |
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| المؤلفون: | Scucchi L., Neri B., Argirò R., Nasso D., Provenzano I., Potenza S., Mossa M., Prete M. D. I., Calabrese E., Petruzziello C., Mauriello A., Monteleone G., Cantonetti M., Biancone L. |
| المساهمون: | Scucchi, L, Neri, B, Argirò, R, Nasso, D, Provenzano, I, Potenza, S, Mossa, M, Prete, Mdi, Calabrese, E, Petruzziello, C, Mauriello, A, Monteleone, G, Cantonetti, M, Biancone, L |
| سنة النشر: | 2020 |
| المجموعة: | Universitá degli Studi di Roma "Tor Vergata": ART - Archivio Istituzionale della Ricerca |
| مصطلحات موضوعية: | Focal lesion, Hepatic follicular lymphoma, Literature review, Crohn’s disease, Rare case, Settore MED/12 - GASTROENTEROLOGIA, Settore MED/08 - ANATOMIA PATOLOGICA, Settore MED/15 - MALATTIE DEL SANGUE, Settore MED/43 - MEDICINA LEGALE |
| الوصف: | OBJECTIVE: Crohn’s Disease (CD) has been associated with non-Hodgkin lymphoma. Follicular Lymphoma (FL) limited to the liver is extremely rare, accounting for 1% to 4.4% of all Primary Hepatic Lymphoma (PHL). CASE PRESENTATION: In 2018, an 85-years old male patient with post-operative recurrence of ileal CD referred rare episodes of fever and mild diffuse abdominal pain. Since cholecystectomy in 2001, clinical history was characterized by recurrent episodes of cholangitis and common bile duct stones. In 2018, ultrasonography and MRI showed a solid focal hepatic lesion (FHL)(4.5 cm x 2.5 cm) in the IV hepatic segment. The radiographic aspect of the lesion was unusual. Initially, focal nodular hyperplasia was suspected. Clinical history of cholangitis and radiological findings subsequently suggested a diagnosis of Hepatic Abscess (HA). A progressive enlargement of the FHL (7.3 cm x 5.8 cm) despite antibiotic treatments, led to perform a liver biopsy. Histological and immunophenotypi-cal analysis of the FHL (7.5 cm x 5.4 cm) enabled a final diagnosis of FL. The “in situ” hybridization for Epstein-Barr virus (EBER) was negative. No additional lesions related to FL were initially detected, thus suggesting a very rare case of PHL in an old patient with CD never treated with thiopurines. CONCLUSIONS: This case report highlights the need to consider a rare diagnosis of FL of the liver in patients showing a challenging focal hepatic lesion of unknown origin. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/wos/WOS:000581569100041; volume:24; issue:19; firstpage:10045; lastpage:10050; numberofpages:6; journal:EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES; http://hdl.handle.net/2108/257166Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85094119130 |
| DOI: | 10.26355/eurrev_202010_23219 |
| الإتاحة: | https://doi.org/10.26355/eurrev_202010_23219Test http://hdl.handle.net/2108/257166Test |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.5F3B3FF2 |
| قاعدة البيانات: | BASE |
| DOI: | 10.26355/eurrev_202010_23219 |
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