التفاصيل البيبلوغرافية
العنوان: |
Functional Anatomy of the Trimer Apex Reveals Key Hydrophobic Constraints That Maintain the HIV-1 Envelope Spike in a Closed State |
المؤلفون: |
Zhang, Peng, Kwon, Alice L., Guzzo, Christina, Liu, Qingbo, Schmeisser, Hana, Miao, Huiyi, Lin, Yin, Cimbro, Raffaello, Huang, Jinghe, Connors, Mark, Schmidt, Stephen D., Dolan, Michael A., Armstrong, Anthony A., Lusso, Paolo |
المساهمون: |
Alter, Galit, Karim, Salim Abdool, Division of Intramural Research, National Institute of Allergy and Infectious Diseases |
المصدر: |
mBio ; volume 12, issue 2 ; ISSN 2150-7511 |
بيانات النشر: |
American Society for Microbiology |
سنة النشر: |
2021 |
الوصف: |
Elucidating the structure and function of the HIV-1 outer envelope proteins is critical for the design of an effective vaccine. Despite the availability of many high-resolution structures, key functional correlates in the envelope trimer remain undefined. |
نوع الوثيقة: |
article in journal/newspaper |
اللغة: |
English |
DOI: |
10.1128/mbio.00090-21 |
DOI: |
10.1128/mBio.00090-21 |
الإتاحة: |
https://doi.org/10.1128/mbio.00090-21Test |
حقوق: |
https://creativecommons.org/licenses/by/4.0Test/ ; https://journals.asm.org/non-commercial-tdm-licenseTest |
رقم الانضمام: |
edsbas.5DFD4EA8 |
قاعدة البيانات: |
BASE |