دورية أكاديمية

Functional Anatomy of the Trimer Apex Reveals Key Hydrophobic Constraints That Maintain the HIV-1 Envelope Spike in a Closed State

التفاصيل البيبلوغرافية
العنوان: Functional Anatomy of the Trimer Apex Reveals Key Hydrophobic Constraints That Maintain the HIV-1 Envelope Spike in a Closed State
المؤلفون: Zhang, Peng, Kwon, Alice L., Guzzo, Christina, Liu, Qingbo, Schmeisser, Hana, Miao, Huiyi, Lin, Yin, Cimbro, Raffaello, Huang, Jinghe, Connors, Mark, Schmidt, Stephen D., Dolan, Michael A., Armstrong, Anthony A., Lusso, Paolo
المساهمون: Alter, Galit, Karim, Salim Abdool, Division of Intramural Research, National Institute of Allergy and Infectious Diseases
المصدر: mBio ; volume 12, issue 2 ; ISSN 2150-7511
بيانات النشر: American Society for Microbiology
سنة النشر: 2021
الوصف: Elucidating the structure and function of the HIV-1 outer envelope proteins is critical for the design of an effective vaccine. Despite the availability of many high-resolution structures, key functional correlates in the envelope trimer remain undefined.
نوع الوثيقة: article in journal/newspaper
اللغة: English
DOI: 10.1128/mbio.00090-21
DOI: 10.1128/mBio.00090-21
الإتاحة: https://doi.org/10.1128/mbio.00090-21Test
حقوق: https://creativecommons.org/licenses/by/4.0Test/ ; https://journals.asm.org/non-commercial-tdm-licenseTest
رقم الانضمام: edsbas.5DFD4EA8
قاعدة البيانات: BASE