دورية أكاديمية
Frailty and post-operative delirium influence on functional status in patients with hip fracture: the GIOG 2.0 study
| العنوان: | Frailty and post-operative delirium influence on functional status in patients with hip fracture: the GIOG 2.0 study |
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| المؤلفون: | Gandossi C. M., Zambon A., Ferrara M. C., Tassistro E., Castoldi G., Colombo F., Mussi C., Martini E., Sergi G., Coin A., Zatti G., Trevisan C., Volpato S., Ungar A., Bellelli G., Lunardelli M. L., Benvenuti E., Maggi S., Pilotto A., Barone A., Zurlo A., Pizzonia M., Antonelli Incalzi R., Residori L., Cena P., Mazzola P., Corsi M., Greco A., Galluccio R., Ricco A., Molteni L., Poli A., Bendini C., Ceccofiglio A., Rubbieri G., Mannarino G., Cartei A., Barghini E., Del Lungo I., Tognelli S., Bandinelli C., Venturelli G., Cella A., Ceolin C., Haxhiaj L., Laudisio A., Bonetto M., Valsecchi M. G. |
| المساهمون: | Gandossi, C. M., Zambon, A., Ferrara, M. C., Tassistro, E., Castoldi, G., Colombo, F., Mussi, C., Martini, E., Sergi, G., Coin, A., Zatti, G., Trevisan, C., Volpato, S., Ungar, A., Bellelli, G., Lunardelli, M. L., Benvenuti, E., Maggi, S., Pilotto, A., Barone, A., Zurlo, A., Pizzonia, M., Antonelli Incalzi, R., Residori, L., Cena, P., Mazzola, P., Corsi, M., Greco, A., Galluccio, R., Ricco, A., Molteni, L., Poli, A., Bendini, C., Ceccofiglio, A., Rubbieri, G., Mannarino, G., Cartei, A., Barghini, E., Del Lungo, I., Tognelli, S., Bandinelli, C., Venturelli, G., Cella, A., Ceolin, C., Haxhiaj, L., Laudisio, A., Bonetto, M., Valsecchi, M. G. |
| سنة النشر: | 2023 |
| المجموعة: | Archivio della ricerca dell'Università di Modena e Reggio Emilia (Unimore: IRIS) |
| مصطلحات موضوعية: | Delirium, Frailty, Functional outcome, Hip fracture, Orthogeriatric |
| الوصف: | Background: This study analyzes the effect of frailty and Post-Operative Delirium (POD) on the functional status at hospital discharge and at 4-month follow-up in patients with hip fracture (HF). Methods: Multicenter prospective observational study of older patients with HF admitted to 12 Italian Orthogeriatric centers (July 2019-August 2022). POD was assessed using the 4AT. A 26-item Frailty Index (FI) was created using data collected on admission. The outcome measures were Cumulated Ambulation Score (CAS) ≤ 2 at discharge and a telephone-administered CAS ≤ 2 after 4months. Poisson regression models were used to assess the effect of frailty and POD on outcomes. Results: 984 patients (median age 84years, IQR = 79–89) were recruited: 480 (48.7%) were frail at admission, 311 (31.6%) developed POD, and 158 (15.6%) had both frailty and POD. In a robust Poisson regression, frailty alone (Relative Risk, RR = 1.56, 95% Confidence Intervals, CI 1.19–2.04, p = 0.001) and its combination with POD (RR = 2.57, 95% CI 2.02–3.26, p < 0.001) were associated with poor functional status at discharge. At 4-month follow-up, the combination of frailty with POD (RR 3.65, 95% CI 1.85–7.2, p < 0.001) increased the risk of poor outcome more than frailty alone (RR 2.38, 95% CI 1.21–4.66, p < 0.001). Conclusions: POD development exacerbates the negative effect that frailty exerts on functional outcomes in HF patients. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/37542601; info:eu-repo/semantics/altIdentifier/wos/WOS:001042782300002; volume:35; issue:11; firstpage:2499; lastpage:2506; journal:AGING CLINICAL AND EXPERIMENTAL RESEARCH; https://hdl.handle.net/11380/1324466Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85167364571 |
| DOI: | 10.1007/s40520-023-02522-8 |
| الإتاحة: | https://doi.org/10.1007/s40520-023-02522-8Test https://hdl.handle.net/11380/1324466Test |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.5A39FFEE |
| قاعدة البيانات: | BASE |
| DOI: | 10.1007/s40520-023-02522-8 |
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