التفاصيل البيبلوغرافية
| العنوان: |
Intraoperative indocyanine green fluorescence imaging to predict early hepatic arterial complications after liver transplantation |
| المؤلفون: |
Terasawa, Muga, Imamura, Hiroshi, Allard, Marc Antoine, Pietrasz, Daniel, Ciacio, Oriana, Pittau, Gabriella, Salloum, Chady, Sa Cunha, Antonio, Cherqui, Daniel, Adam, René, Azoulay, Daniel, Saiura, Akio, Vibert, Eric, Golse, Nicolas |
| المصدر: |
Liver Transplantation ; ISSN 1527-6465 |
| بيانات النشر: |
Ovid Technologies (Wolters Kluwer Health) |
| سنة النشر: |
2024 |
| الوصف: |
The purpose of this study was to propose an innovative intraoperative criterion in a liver transplantation setting that would judge arterial flow abnormality that may lead to early hepatic arterial occlusion, that is, thrombosis or stenosis, when left untreated and to carry out reanastomosis. After liver graft implantation, and after ensuring that there is no abnormality on the Doppler ultrasound (qualitative and quantitative assessment), we intraoperatively injected indocyanine green dye (0.01 mg/Kg), and we quantified the fluorescence signal at the graft pedicle using ImageJ software. From the obtained images of 89 adult patients transplanted in our center between September 2017 and April 2019, we constructed fluorescence intensity curves of the hepatic arterial signal and examined their relationship with the occurrence of early hepatic arterial occlusion (thrombosis or stenosis). Early hepatic arterial occlusion occurred in 7 patients (7.8%), including 3 thrombosis and 4 stenosis. Among various parameters of the flow intensity curve analyzed, the ratio of peak to plateau fluorescence intensity and the jagged wave pattern at the plateau phase were closely associated with this dreaded event. By combining the ratio of peak to plateau at 0.275 and a jagged wave, we best predicted the occurrence of early hepatic arterial occlusion and thrombosis, with sensitivity/specificity of 0.86/0.98 and 1.00/0.94, respectively. Through a simple composite parameter, the indocyanine green fluorescence imaging system is an additional and promising intraoperative modality for identifying recipients of transplant at high risk of developing early hepatic arterial occlusion. This tool could assist the surgeon in the decision to redo the anastomosis despite normal Doppler ultrasonography. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| DOI: |
10.1097/lvt.0000000000000355 |
| DOI: |
10.1097/LVT.0000000000000355 |
| الإتاحة: |
https://doi.org/10.1097/lvt.0000000000000355Test |
| رقم الانضمام: |
edsbas.58A14AC9 |
| قاعدة البيانات: |
BASE |
