التفاصيل البيبلوغرافية
| العنوان: |
Alternative nighttime nutrition regimens in glycogen storage disease type I: a controlled crossover study |
| المؤلفون: |
Hochuli, Michel, Christ, Emanuel, Meienberg, Fabian, Lehmann, Roger, Krützfeldt, Jan, Baumgartner, Matthias |
| سنة النشر: |
2021 |
| المجموعة: |
réro doc Digital Library (Library Network of Western Switzerland / Réseau des bibliothèques de Suisse occidentale) |
| الوصف: |
Background: Traditional approaches for nighttime glycemic control in glycogen storage disease type I (GSDI) include continuous tube feeding, or ingestion of uncooked corn starch (CS) at bedtime. A modified corn starch (MCS) has been shown to prolong euglycemia in some patients. The aim of this study was to evaluate whether stable nighttime glucose control can be achieved with other types of slowly digested carbohydrates in adult GSDI patients. Methods: In this cross-over study, nocturnal glucose control and fasting times were assessed with three different nocturnal nutrition regimens in five patients, using continuous glucose monitoring (CGMS) in an outpatient everyday life setting. For each patient, continuous glucose profiles were measured after ingestion of (1) CS, (2) MCS or (3) a pasta meal at bedtime, during 5 to 6 consecutive nights for each regimen. Results: Stable nocturnal glucose control was achieved for all patients with a pasta meal, with a mean duration of glycemia >3.5mmol/l of 7.6h (range 5.7-10.8), and >4mmol/l of 7h (5.2-9.2), similar to CS and MCS. Fasting glucose before breakfast on workdays (after 7.1 ± 0.8h) was not significantly different between the three interventions (CS 4.1 ± 0.5mmol/l, MCS 4.6 ± 0.7mmol/l, pasta 4.3 ± 0.9mmol/l). During prolonged fasting on weekends, longer duration of normoglycemia was achieved with CS or MCS than with pasta. Conclusion: Consumption of cooked pasta is a suitable and more palatable alternative to uncooked corn starch to achieve nighttime glucose control in adult patients with GSDI. |
| نوع الوثيقة: |
other/unknown material |
| اللغة: |
English |
| العلاقة: |
http://doc.rero.ch/record/332170/files/10545_2015_Article_9864.pdfTest |
| الإتاحة: |
http://doc.rero.ch/record/332170/files/10545_2015_Article_9864.pdfTest |
| رقم الانضمام: |
edsbas.5628CDBD |
| قاعدة البيانات: |
BASE |
