دورية أكاديمية
Safety of allergen immunotherapy in patients with SARS-CoV-2 infection
| العنوان: | Safety of allergen immunotherapy in patients with SARS-CoV-2 infection |
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| المؤلفون: | ATAYIK, Emel, AYTEKİN, Gökhan |
| المصدر: | Volume: 8, Issue: 5 642-649 ; 2149-3189 ; The European Research Journal |
| بيانات النشر: | Prusa Medical Publishing Prusa Medikal Yayıncılık |
| سنة النشر: | 2022 |
| المجموعة: | DergiPark Akademik (E-Journals) |
| مصطلحات موضوعية: | Allergic rhinitis, allergy immunotherapy, subcutaneous immunotherapy, therapeutics, Alerji, Allergy |
| الوصف: | Objectives: The aims of presenting study were trying to expose the course of SARS-CoV-2 (severe acute respiratory syndrome–related coronavirus) in patients with allergic rhinitis (AR), to compare the prevalence of SARS-CoV-2 infection, hospitalization and pneumonia rates in patients with AR receiving allergen immunotherapy (AIT) and patients did not receiving AIT (non-receivers) and to define possible risk factors for SARS-CoV-2 positivity in patients with AR.Methods: A total of 419 patients with AR who were being followed-up in a tertiary allergy clinic between June 1, 2020 and December 31, 2020, were selected for the study. Results: Seventy-nine (18.9%) patients became infected with the SARS-CoV-2 [32 (19.6%) patients in AR patients with AIT and 47 (18.4%) patients in non-receivers] and the rate of pneumonia was 2.4% [12.7% of SARS-CoV-2 (+) patients]. There was no significant difference was determined between the AR patients with AIT and the non-receivers in regard of the rate of SARS-CoV-2 infection, pneumonia and hospitalization (p = 0.864, p = 0.055 and p = 0.075; respectively). There was a significant difference between the groups in terms of gender, duration of disease, sensitivity to allergens (atopy) and serum IgE levels (p = 0.009, p = 0.001, p = 0.001 and p = 0.001; respectively). The accompanying comorbidities, eosinophil cout, AIT and duration of AIT were not found to be associated with an increased risk SARS-CoV-2 PCR positivity. However, female gender was shown to be associated with an decreased risk for SARS-CoV-2 PCR positivity (OR, 0.571; 95% confidence interval, 0.330-0.987; p = 0.045).Conclusions: The course of SARS-CoV-2 is similar in patients with AR who underwent AIT and patients with AR who did not undergo AIT, and AIT does not seem to increase the risk for SARS-CoV-2 infection. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | https://dergipark.org.tr/tr/download/article-file/2304600Test; https://dergipark.org.tr/tr/pub/eurj/issue/72215/1086549Test |
| DOI: | 10.18621/eurj.1086549 |
| الإتاحة: | https://doi.org/10.18621/eurj.1086549Test https://dergipark.org.tr/tr/pub/eurj/issue/72215/1086549Test |
| رقم الانضمام: | edsbas.53A4B78 |
| قاعدة البيانات: | BASE |
| DOI: | 10.18621/eurj.1086549 |
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