التفاصيل البيبلوغرافية
| العنوان: |
Comparison of frozen and permanent section diagnosis in ovarian neoplasms: Analysis of factors affecting accuracy |
| المؤلفون: |
Akbarzadeh-Jahromi, Mojgan, Sari Aslani, Fatemeh, Raeisi Shahraki, Hadi, Momtahan, Mozhdeh, Taheri, Negar |
| بيانات النشر: |
Lippincott Williams and Wilkins |
| سنة النشر: |
2021 |
| المجموعة: |
Shahrekord University Of Medical Sciences: Research information management system |
| مصطلحات موضوعية: |
WQ Obstetrics, QZ pathology-Neoplasms |
| الوصف: |
Ovarian cancer is the seventh most common form of cancer among women worldwide. The aim of the study was to determine the accuracy of a frozen section and the factors affecting the accuracy of frozen diagnosis of ovarian neoplasms. This retrospective, cross-sectional study was conducted on 401 patients with ovarian masses with frozen section diagnosis in Shahid Faghihi Hospital affiliated to Shiraz University of Medical Sciences between 2014 and 2018. Each ovarian tumor sample was evaluated for histopathologic diagnosis using frozen and paraffin-embedded sections, which were reviewed by an expert gynecologic pathologist. Accuracy and diagnostic values were estimated by comparing the results of the 2 techniques, using the paraffin section as the gold standard. The overall accuracy of the frozen section was 94.5. Its sensitivity was 85.3 for malignant, 88.2 for borderline, and 99.6 for benign tumors. Its specificity was also 99.7 for malignant, 98.0 for borderline, and 90.9 for benign tumors. The positive predictive value was 98.9 for malignant, 86.5 for borderline, and 94.6 for benign tumors. Most false negatives occurred in mucinous and borderline tumors. The sensitivity of malignant tumors of germ cell and sex cord-stromal cell types were 64.3 and 95.5, respectively. The specificity of germ cell and sex-cord stromal tumors were 100 and 93.8, respectively. Frozen section seems to be a precise technique for histopathologic diagnosis of ovarian tumors. However, borderline and mucinous tumors are the most problematic issues during frozen section diagnosis and malignant germ cell tumors have the lowest sensitivity. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
unknown |
| العلاقة: |
Akbarzadeh-Jahromi, Mojgan and Sari Aslani, Fatemeh and Raeisi Shahraki, Hadi and Momtahan, Mozhdeh and Taheri, Negar (2021) Comparison of frozen and permanent section diagnosis in ovarian neoplasms: Analysis of factors affecting accuracy. International Journal of Gynecological Pathology. ISSN 02771691 |
| الإتاحة: |
http://eprints.skums.ac.ir/9199Test/ |
| رقم الانضمام: |
edsbas.5376DEC9 |
| قاعدة البيانات: |
BASE |
